Retrospective Cohort Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Sep 28, 2017; 9(9): 350-358
Published online Sep 28, 2017. doi: 10.4329/wjr.v9.i9.350
Clinical significance of prostate 18F-labelled fluorodeoxyglucose uptake on positron emission tomography/computed tomography: A five-year review
Madhurima R Chetan, Tristan Barrett, Ferdia A Gallagher
Madhurima R Chetan, School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, United Kingdom
Tristan Barrett, Ferdia A Gallagher, Department of Radiology, Addenbrooke’s Hospital and University of Cambridge, Cambridge CB2 0QQ, United Kingdom
Author contributions: Chetan MR, Barrett T and Gallagher FA designed the research; Chetan MR performed the research; Chetan MR, Barrett T and Gallagher FA analysed the data; Chetan MR wrote the paper; Barrett T and Gallagher FA critically revised the manuscript for important intellectual content.
Institutional review board statement: The study was reviewed and approved by Addenbrooke’s Hospital, Cambridge.
Informed consent statement: The requirement for informed consent for data analysis was waived.
Conflict-of-interest statement: The authors have no competing interests.
Data sharing statement: No additional data available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Tristan Barrett, MB BS, BSc, MRCP, FRCR, Department of Radiology, Addenbrooke’s Hospital and University of Cambridge, Box 218, Cambridge CB2 0QQ, United Kingdom.
Telephone: +44-1223-336890 Fax: +44-1223-330915
Received: September 20, 2016
Peer-review started: September 23, 2016
First decision: November 21, 2016
Revised: February 20, 2017
Accepted: March 21, 2017
Article in press: March 22, 2017
Published online: September 28, 2017
Core Tip

Core tip:18F-labelled fluorodeoxyglucose (18F-FDG) uptake overlaps significantly between malignant and benign prostatic conditions. In a cohort of nearly 3000 patients over a 5-year period, the reporting of incidental elevated prostatic 18F-FDG uptake did not affect subsequent clinical management or patient outcomes.