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World J Radiol. Jun 28, 2022; 14(6): 114-136
Published online Jun 28, 2022. doi: 10.4329/wjr.v14.i6.114
Tuberculosis conundrum - current and future scenarios: A proposed comprehensive approach combining laboratory, imaging, and computing advances
Suleman Adam Merchant, Mohd Javed Saifullah Shaikh, Prakash Nadkarni
Suleman Adam Merchant, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai 400022, Maharashtra, India
Mohd Javed Saifullah Shaikh, Department of Radiology, North Bengal Neuro Centre, Jupiter magnetic resonance imaging, Diagnostic Centre, Siliguri 734003, West Bengal, India
Prakash Nadkarni, College of Nursing, University of Iowa, Iowa 52242, IA, United States
Author contributions: Merchant SA conceptualized the article; all authors wrote, read and approved the final manuscript.
Conflict-of-interest statement: All authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Suleman Adam Merchant, MBBS, MD, Former Dean, Professor & Head (Radiology), Lokmanya Tilak Municipal Medical College and General Hospital, Sion Hospital, Mumbai 400022, Maharashtra, India.
Received: January 17, 2022
Peer-review started: January 17, 2022
First decision: March 16, 2022
Revised: April 17, 2022
Accepted: May 27, 2022
Article in press: May 27, 2022
Published online: June 28, 2022
Core Tip

Core Tip: A Holistic (comprehensive) approach is suggested to achieve tuberculosis (TB) elimination goals. Early diagnosis especially for Multi-Drug Resistant TB. Utility of Modern Rapid Diagnostic Tools. The role of Imaging in TB and key radiological signs. Comprehensive Artificial Intelligence(AI) algorithms incorporating key Imaging and clinical signs. The role of Vitamin D supplementation in complementing the TB drug regimen. Molecular Imaging. Quantum Computing and other perspectives in TB strategies to help achieve the various targets set for elimination of TB. A unified Global approach with edge computing/ dashboards and other technological innovations.