Reproducibility of thrombus volume quantification in multicenter computed tomography pulmonary angiography studies
Audrey E Kaufman, Alison N Pruzan, Sarayu Ramachandran, Adam Jacobi, Indravadan Patel, Lee Schwocho, Michele F Mercuri, Zahi A Fayad, Venkatesh Mani, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States
Audrey E Kaufman, Alison N Pruzan, Sarayu Ramachandran, Zahi A Fayad, Venkatesh Mani, Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, Hess Center for Science and Medicine, New York, NY 10029, United States
Ching Hsu, Indravadan Patel, Lee Schwocho, Michele F Mercuri, Daiichi Sankyo Inc., Basking Ridge, NJ 07920, United States
Author contributions: All authors designed the experiment; Kaufman AE, Pruzan AN, Ramachandran S, Mani V performed the experiment; Kaufman AE and Pruzan AN performed the image analysis; Hsu C, Pruzan AN and Mani V performed statistical analysis; Kaufman AE and Mani V wrote the draft of the manuscript; all authors critically reviewed the manuscript.
Institutional review board statement: This study was submitted to the Institutional Review Board (IRB) of the Icahn School of Medicine at Mount Sinai but was deemed that no IRB approval was necessary for conduct of this study [See Determination regarding engagement in human research letter from the program for protection of research subjects (PPHS) office IRB].
Informed consent statement: Waiver of informed consent was obtained from the Institutional Review Board as only deidentified data was used in this study. The images analyzed for this study were anonymized and devoid of any Protected Health Information.
Conflict-of-interest statement: Ching Hsu, Indravadan Patel, Lee Schwocho, Michele F Mercuri are employees of Daiichi Sankyo Inc. All other authors have no conflicts to disclose.
Data sharing statement: Once published and after appropriate safeguard to ensure that the data is devoid of any identifiers, the data used for the analysis for this study will be shared on the Mount Sinai data sharing portal according to Institutional guidelines.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Venkatesh Mani, PhD, Associate Professor, Department of Radiology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, United States. firstname.lastname@example.org
Telephone: +1-212-8248454 Fax: +1-646-5379589
Received: June 1, 2018
Peer-review started: June 1, 2018
First decision: July 23, 2018
Revised: July 27, 2018
Accepted: August 4, 2018
Article in press: August 4, 2018
Published online: October 28, 2018