Battal B, Ince S, Akgun V, Kocaoglu M, Ozcan E, Tasar M. Malformations of cortical development: 3T magnetic resonance imaging features. World J Radiol 2015; 7(10): 329-335 [PMID: 26516429 DOI: 10.4329/wjr.v7.i10.329]
Corresponding Author of This Article
Bilal Battal, MD, Department of Radiology, Gulhane Military Medical School, General Doktor Tevfik Saglam Caddesi, 06018 Etlik, Ankara, Turkey. bilbat_23@yahoo.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Radiol. Oct 28, 2015; 7(10): 329-335 Published online Oct 28, 2015. doi: 10.4329/wjr.v7.i10.329
Malformations of cortical development: 3T magnetic resonance imaging features
Bilal Battal, Selami Ince, Veysel Akgun, Murat Kocaoglu, Emrah Ozcan, Mustafa Tasar
Bilal Battal, Selami Ince, Veysel Akgun, Murat Kocaoglu, Emrah Ozcan, Mustafa Tasar, Department of Radiology, Gulhane Military Medical School, 06018 Etlik, Ankara, Turkey
Murat Kocaoglu, Department of Radiology, Near East University, Faculty of Medicine, Nicosia, North Cyprus, Turkey
Author contributions: Battal B, Ince S, Akgun V, Ozcan E and Kocaoglu M designed and collected data; Battal B, Ince S and Akgun V written of the article; Battal B, Kocaoglu M and Tasar M reviewed and supervised the manuscript.
Conflict-of-interest statement: The authors declare no conflict of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Bilal Battal, MD, Department of Radiology, Gulhane Military Medical School, General Doktor Tevfik Saglam Caddesi, 06018 Etlik, Ankara, Turkey. bilbat_23@yahoo.com
Telephone: +90-533-4330667 Fax: +90-312-3260551
Received: April 26, 2015 Peer-review started: May 11, 2015 First decision: June 24, 2015 Revised: July 31, 2015 Accepted: August 20, 2015 Article in press: August 21, 2015 Published online: October 28, 2015
Abstract
Malformation of cortical development (MCD) is a term representing an inhomogeneous group of central nervous system abnormalities, referring particularly to embriyological aspect as a consequence of any of the three developmental stages, i.e., cell proliferation, cell migration and cortical organization. These include cotical dysgenesis, microcephaly, polymicrogyria, schizencephaly, lissencephaly, hemimegalencephaly, heterotopia and focal cortical dysplasia. Since magnetic resonance imaging is the modality of choice that best identifies the structural anomalies of the brain cortex, we aimed to provide a mini review of MCD by using 3T magnetic resonance scanner images.
Core tip: Malformations of cortical development reflect embryological disruptions in neuronal proliferation, neuronal migration, cortical organization or multiple steps of the cortical development. Malformation of cortical development (MCDs) are important causes of refractory epilepsy. Magnetic resonance imaging including the advanced MRI techniques has a pivotal role in diagnosis of MCDs and prediction of feasibility of surgical management in cases that are refractory to medication.
