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Spontaneous ovarian hyperstimulation syndrome and pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism
Rene Epunza Kanza, Isabelle Rousseau, Edith Bordeleau, Michel Berube, Department of Radiology, Chicoutimi Hospital, Saguenay, Quebec G7H5H6, Canada
Rene Epunza Kanza, Department of Radiology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, Quebec J1H5N4, Canada
Sylvain Gagnon, Department of Gynecology, Chicoutimi Hospital, Saguenay, Quebec G7H5H6, Canada
Helene Villeneuve, Department of Endocrinology, Chicoutimi Hospital, Saguenay, Quebec G7H5H6, Canada
David Laverdiere, Department of Internal Medicine, Chicoutimi Hospital, Saguenay, Quebec G7H5H6, Canada
Author contributions: Kanza RE performed the diagnosis and wrote the manuscript; Gagnon S was involved in performing the diagnosis and in patient care; Villeneuve H was involved in performing the diagnosis and patient care, and contributed to endocrine follow-up; Laverdiere D was involved in diagnosis and patient care; Bordeleau E performed pelvic ultrasound; Rousseau I and Berube M were involved in critical revision of the manuscript.
Correspondence to: Dr. Rene Epunza Kanza, MD, PhD, Clinical Assistant Professor, Department of Radiology, Chicoutimi Hospital affiliated with Sherbrooke University, 305 Rue Saint-Vallier, Saguenay, Quebec G7H5H6, Canada. rn.kn.01@gmail.com
Telephone: +1-418-5411234 Fax: +1-418-5435104
Received: May 14, 2012
Revised: August 21, 2012
Accepted: August 28, 2012
Published online: January 28, 2013
Revised: August 21, 2012
Accepted: August 28, 2012
Published online: January 28, 2013
Abstract
We report an unusual case of spontaneous ovarian hyperstimulation syndrome and pituitary hyperplasia mimicking macroadenoma in an adult, non-pregnant woman. Her condition was triggered by unrecognized primary hypothyroidism, which regressed after thyroid hormone replacement therapy. This case highlights the need for clinicians and radiologists to familiarize themselves with the clinical and imaging features detected in case of these complications of primary hypothyroidism, which are not well known in the medical and radiological profession. Such improved knowledge will help avoid delays in diagnosis, progression to life-threatening complications, and unnecessary surgery.
Keywords: Ovarian hyperstimulation syndrome, Pituitary hyperplasia, Magnetic resonance imaging, Hypothyroidism