Review
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World J Radiol. Mar 28, 2010; 2(3): 103-108
Published online Mar 28, 2010. doi: 10.4329/wjr.v2.i3.103
Recent advances in breast cancer radiotherapy: Evolution or revolution, or how to decrease cardiac toxicity?
Youlia M Kirova
Youlia M Kirova, Radiation Oncology, Institut Curie 26, Rue d’Ulm, 75005 Paris, France
Author contributions: Kirova YM solely wrote this paper.
Correspondence to: Dr. Youlia M Kirova, Radiation Oncology, Institut Curie 26, Rue d’Ulm, 75005 Paris, France. youlia.kirova@curie.net
Telephone: +33-1-44324637 Fax: +33-1-44324616
Received: February 6, 2010
Revised: March 1, 2010
Accepted: March 9, 2010
Published online: March 28, 2010
Abstract

Radiation therapy has a major role in the management of breast cancers. However, there is no consensus on how to irradiate and on volume definitions, and there are strong differences in strategies according to different centers and physicians. New treatment protocols and techniques have been used with the principal purpose of decreasing lung and heart toxicity and adapting radiation treatment to patients’ anatomy. There is evidence that indicates internal mammary chain radiotherapy should be used carefully and that high quality techniques should be used for decreasing the dose delivered to the heart. This review of the literature presents the state of the art on breast cancer radiotherapy, with special focus on the indications, techniques, and potential toxicity.

Keywords: Cardiac toxicity, Ejection fraction, Breast cancer, Radiotherapy, Chemotherapy, Herceptin