Case Report
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World J Radiol. Oct 28, 2010; 2(10): 405-409
Published online Oct 28, 2010. doi: 10.4329/wjr.v2.i10.405
Multiple progressive focal nodular hyperplasia lesions of liver in a patient with hemosiderosis
Arda Kayhan, Nanda Venu, Hatice Lakadamyalı, Donald Jensen, Aytekin Oto
Arda Kayhan, Department of Radiology, Namık Kemal University, Tekirdağ 59100, Turkey
Nanda Venu, Donald Jensen, Department of Gastroenterology, University of Chicago, Chicago, IL 60637, United States
Hatice Lakadamyalı, Department of Radiology, Başkent University, Alanya 07400, Turkey
Aytekin Oto, Department of Radiology, University of Chicago, Chicago, IL 60637, United States
Author contributions: Kayhan A drafted the article and approved the final version; Venu N prepared the paper initially; Lakadamyalı H reviewed the literature; Jensen D contributed to the conception and design; Oto A revised the manuscript critically for important intellectual content.
Correspondence to: Arda Kayhan, MD, Department of Radiology, Namık Kemal University, 100. yıl mahallesi, Tunca caddesi, No. 32, Tekirdağ 59100, Turkey. arda_kayhan@yahoo.com
Telephone: +90-282-2620130 Fax: + 90-282-2620310
Received: July 2, 2010
Revised: August 27, 2010
Accepted: September 3, 2010
Published online: October 28, 2010
Abstract

Focal nodular hyperplasia (FNH) is the second most common benign lesion of the liver. It is a solitary lesion and usually does not enlarge. We present the magnetic resonance imaging findings of multiple progressive FNH lesions in a patient with hemosiderosis using Gadolinium-EOB-DTPA (Eovist) as a hepatobiliary contrast agent. The possible mechanisms underlying the occurrence and progression of FNH lesions and the potential value of Eovist in characterizing the lesions were discussed.

Keywords: Focal nodular hyperplasia, Hemosiderosis, Magnetic resonance imaging, Gadolinium-EOB-DTPA