Reference Citation Analysis: Find an Article, Find a Category, Find a Journal, Find a Scholar

For: Rimola J, Forner A, Tremosini S, Reig M, Vilana R, Bianchi L, Rodríguez-Lope C, Solé M, Ayuso C, Bruix J. Non-invasive diagnosis of hepatocellular carcinoma ≤ 2 cm in cirrhosis. Diagnostic accuracy assessing fat, capsule and signal intensity at dynamic MRI. J Hepatol 2012;56:1317-23. [PMID: 22314420 DOI: 10.1016/j.jhep.2012.01.004] [Citation(s) in RCA: 139] [Impact Index Per Article: 10.7] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/17/2011] [Revised: 12/30/2011] [Accepted: 01/05/2012] [Indexed: 12/13/2022]

For:	Rimola J, Forner A, Tremosini S, Reig M, Vilana R, Bianchi L, Rodríguez-Lope C, Solé M, Ayuso C, Bruix J. Non-invasive diagnosis of hepatocellular carcinoma ≤ 2 cm in cirrhosis. Diagnostic accuracy assessing fat, capsule and signal intensity at dynamic MRI. J Hepatol 2012;56:1317-23. [PMID: 22314420 DOI: 10.1016/j.jhep.2012.01.004] [Citation(s) in RCA: 139] [Impact Index Per Article: 10.7] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/17/2011] [Revised: 12/30/2011] [Accepted: 01/05/2012] [Indexed: 12/13/2022]

Number

Cited by Other Article(s)

Moris D, Martinino A, Schiltz S, Allen PJ, Barbas A, Sudan D, King L, Berg C, Kim C, Bashir M, Palta M, Morse MA, Lidsky ME. Advances in the treatment of hepatocellular carcinoma: An overview of the current and evolving therapeutic landscape for clinicians. CA Cancer J Clin 2025. [PMID: 40392748 DOI: 10.3322/caac.70018] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/25/2024] [Revised: 04/10/2025] [Accepted: 04/11/2025] [Indexed: 05/22/2025] Open

Yahia Y, Qasem M, Abbarh S, Saffo H, Obeidat IM, Barjas HH, Faisal MM, Halabiya M, Chandra P, Derbala M. Risk of Malignancy in Indeterminate Liver Nodules Among Patients with Cirrhosis: A Retrospective Cohort Study. J Gastrointest Cancer 2024;56:1. [PMID: 39414724 PMCID: PMC11485135 DOI: 10.1007/s12029-024-01122-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 09/29/2024] [Indexed: 10/18/2024]

Kazi IA, Jahagirdar V, Kabir BW, Syed AK, Kabir AW, Perisetti A. Role of Imaging in Screening for Hepatocellular Carcinoma. Cancers (Basel) 2024;16:3400. [PMID: 39410020 PMCID: PMC11476228 DOI: 10.3390/cancers16193400] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/31/2024] [Revised: 09/22/2024] [Accepted: 09/26/2024] [Indexed: 10/20/2024] Open

Afyouni S, Zandieh G, Nia IY, Pawlik TM, Kamel IR. State-of-the-art imaging of hepatocellular carcinoma. J Gastrointest Surg 2024;28:1717-1725. [PMID: 39117267 DOI: 10.1016/j.gassur.2024.08.001] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/07/2024] [Revised: 07/20/2024] [Accepted: 08/01/2024] [Indexed: 08/10/2024]

Liang Y, Wu H, Wei X. Development and validation of a CT-based nomogram for accurate hepatocellular carcinoma detection in high risk patients. Front Oncol 2024;14:1374373. [PMID: 39165686 PMCID: PMC11333883 DOI: 10.3389/fonc.2024.1374373] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/22/2024] [Accepted: 07/18/2024] [Indexed: 08/22/2024] Open

Chiu KWH, Chiang CL, Chan KSK, Hui Y, Ren J, Wei X, Ng KS, Lee HFV, Chia NH, Cheung TT, Chan S, Chan ACY, Ng KCK, Seto WKW, Khong PL, Kong FM. Dual-tracer PET/CT in the management of hepatocellular carcinoma. JHEP Rep 2024;6:101099. [PMID: 38974366 PMCID: PMC11225831 DOI: 10.1016/j.jhepr.2024.101099] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/09/2023] [Revised: 04/05/2024] [Accepted: 04/15/2024] [Indexed: 07/09/2024] Open

Abstract

Background & Aims

Combined 18F-fluorodeoxyglucose (FDG) and 11C-acetate (dual-tracer) positron-emission tomography/computed tomography (PET/CT) is being increasingly performed for the management of hepatocellular carcinoma (HCC), although its role is not well defined. Therefore, we evaluated its effectiveness in (i) staging, (ii) characterization of indeterminate lesions on conventional imaging, and (iii) detection of HCC in patients with unexplained elevations in serum alpha-fetoprotein (AFP) levels.

Methods

We retrospectively assessed 525 consecutive patients from three tertiary centers between 2014 and 2020. For staging, we recorded new lesion detection rates, changes in the Barcelona Clinic Liver Cancer (BCLC) classification, and treatment allocation due to dual-tracer PET/CT. To characterize indeterminate lesions and unexplained elevation of serum AFP levels, the sensitivity and specificity of dual-tracer PET/CT in diagnosing HCC were evaluated. A multidisciplinary external review and a cost-benefit analysis of patients for metastatic screening were also performed.

Results

Dual-tracer PET/CT identified new lesions in 14.3% of 273 staging patients, resulting in BCLC upstaging in 11.7% and treatment modifications in 7.7%. It upstaged 8.1% of 260 patients undergoing metastatic screening, with estimated savings of US$495 per patient. It had a sensitivity and specificity of 80.7% (95% CI 71.2-88.6%) and 94.8% (95% CI 90.4-98.6%), respectively, for diagnosing HCC in 201 indeterminate lesions. It detected HCC in 45.1% of 51 patients with unexplained elevations in serum AFP concentrations. External review revealed substantial agreement between local and external image interpretation and patient assessment (n = 273, κ = 0.822; 95% CI 0.803-0.864).

Conclusions

Dual-tracer PET/CT provides added value beyond conventional imaging in patients with HCC by improving staging, confirming HCC diagnosis with high accuracy in patients with indeterminate lesions, and detecting HCC in patients with unexplained elevation of serum AFP.

Impact and implications

Compared to CT or MRI, dual-tracer positron-emission tomography/computed tomography (PET/CT) led to upstaging in 12% of patients with hepatocellular carcinoma (HCC) undergoing staging, resulting in treatment modification in 8% of cases and a cost saving of US$495 per patient. It also accurately detected HCC in high-risk cases where CT or MRI were equivocal or normal. Dual-tracer PET/CT provides added value beyond conventional imaging in patients with HCC by improving staging, confirming HCC diagnosis with high accuracy in patients with indeterminate lesions, and detecting HCC in patients with unexplained elevation of serum AFP.

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Ma Y, Gong Y, Qiu Q, Ma C, Yu S. Research on multi-model imaging machine learning for distinguishing early hepatocellular carcinoma. BMC Cancer 2024;24:363. [PMID: 38515051 PMCID: PMC10956394 DOI: 10.1186/s12885-024-12109-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/19/2023] [Accepted: 03/12/2024] [Indexed: 03/23/2024] Open

Abstract

OBJECTIVE

To investigate the value of differential diagnosis of hepatocellular carcinoma (HCC) and non-hepatocellular carcinoma (non-HCC) based on CT and MR multiphase radiomics combined with different machine learning models and compare the diagnostic efficacy between different radiomics models.

BACKGROUND

Primary liver cancer is one of the most common clinical malignancies, hepatocellular carcinoma (HCC) is the most common subtype of primary liver cancer, accounting for approximately 90% of cases. A clear diagnosis of HCC is important for the individualized treatment of patients with HCC. However, more sophisticated diagnostic modalities need to be explored.

METHODS

This retrospective study included 211 patients with liver lesions: 97 HCC and 124 non-hepatocellular carcinoma (non-HCC) who underwent CT and MRI. Imaging data were used to obtain imaging features of lesions and radiomics regions of interest (ROI). The extracted imaging features were combined to construct different radiomics models. The clinical data and imaging features were then combined with radiomics features to construct the combined models. Support Vector Machine (SVM), K-nearest Neighbor (KNN), RandomForest (RF), eXtreme Gradient Boosting (XGBoost), Light Gradient Boosting Machine (LightGBM), Multilayer Perceptron (MLP) six machine learning models were used for training. Five-fold cross-validation was used to train the models, and ROC curves were used to analyze the diagnostic efficacy of each model and calculate the accuracy rate. Model training and efficacy test were performed as before.

RESULTS

Statistical analysis showed that some clinical data (gender and concomitant cirrhosis) and imaging features (presence of envelope, marked enhancement in the arterial phase, rapid contouring in the portal phase, uniform density/signal and concomitant steatosis) were statistical differences (P < 0.001). The results of machine learning models showed that KNN had the best diagnostic efficacy. The results of the combined model showed that SVM had the best diagnostic efficacy, indicating that the combined model (accuracy 0.824) had better diagnostic efficacy than the radiomics-only model.

CONCLUSIONS

Our results demonstrate that the radiomic features of CT and MRI combined with machine learning models enable differential diagnosis of HCC and non-HCC (malignant, benign). The diagnostic model with dual radiomic had better diagnostic efficacy. The combined model was superior to the radiomic model alone.

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Yao WW, Zhang HW, M YP, Lee JM, Lee RT, Wang YL, Liu XL, Shen XP, Huang B, Lin F. Comparison of the Ability of Gadobenate Dimeglumine and Gadolinium Ethoxybenzyl Dimeglumine to Display the major Features for Noninvasively Diagnosing Hepatocellular Carcinoma According to the LI-RADS 2018v. Technol Cancer Res Treat 2024;23:15330338241260331. [PMID: 38860337 PMCID: PMC11168249 DOI: 10.1177/15330338241260331] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 06/12/2024] Open

Kupczyk PA, Kurt D, Endler C, Luetkens JA, Kukuk GM, Fronhoffs F, Fischer HP, Attenberger UI, Pieper CC. MRI proton density fat fraction for estimation of tumor grade in steatotic hepatocellular carcinoma. Eur Radiol 2023;33:8974-8985. [PMID: 37368108 PMCID: PMC10667464 DOI: 10.1007/s00330-023-09864-x] [Citation(s) in RCA: 6] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/12/2023] [Revised: 04/03/2023] [Accepted: 05/15/2023] [Indexed: 06/28/2023]

Abstract

OBJECTIVES

Image-based detection of intralesional fat in focal liver lesions has been established in diagnostic guidelines as a feature indicative of hepatocellular carcinoma (HCC) and associated with a favorable prognosis. Given recent advances in MRI-based fat quantification techniques, we investigated a possible relationship between intralesional fat content and histologic tumor grade in steatotic HCCs.

METHODS

Patients with histopathologically confirmed HCC and prior MRI with proton density fat fraction (PDFF) mapping were retrospectively identified. Intralesional fat of HCCs was assessed using an ROI-based analysis and the median fat fraction of steatotic HCCs was compared between tumor grades G1-3 with non-parametric testing. ROC analysis was performed in case of statistically significant differences (p < 0.05). Subgroup analyses were conducted for patients with/without liver steatosis and with/without liver cirrhosis.

RESULTS

A total of 57 patients with steatotic HCCs (62 lesions) were eligible for analysis. The median fat fraction was significantly higher for G1 lesions (median [interquartile range], 7.9% [6.0─10.7%]) than for G2 (4.4% [3.2─6.6%]; p = .001) and G3 lesions (4.7% [2.8─7.8%]; p = .036). PDFF was a good discriminator between G1 and G2/3 lesions (AUC .81; cut-off 5.8%, sensitivity 83%, specificity 68%) with comparable results in patients with liver cirrhosis. In patients with liver steatosis, intralesional fat content was higher than in the overall sample, with PDFF performing better in distinguishing between G1 and G2/3 lesions (AUC .92; cut-off 8.8%, sensitivity 83%, specificity 91%).

CONCLUSIONS

Quantification of intralesional fat using MRI PDFF mapping allows distinction between well- and less-differentiated steatotic HCCs.

CLINICAL RELEVANCE

PDFF mapping may help optimize precision medicine as a tool for tumor grade assessment in steatotic HCCs. Further investigation of intratumoral fat content as a potential prognostic indicator of treatment response is encouraged.

KEY POINTS

• MRI proton density fat fraction mapping enables distinction between well- (G1) and less- (G2 and G3) differentiated steatotic hepatocellular carcinomas. • In a retrospective single-center study with 62 histologically proven steatotic hepatocellular carcinomas, G1 tumors showed a higher intralesional fat content than G2 and G3 tumors (7.9% vs. 4.4% and 4.7%; p = .004). • In liver steatosis, MRI proton density fat fraction mapping was an even better discriminator between G1 and G2/G3 steatotic hepatocellular carcinomas.

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Shahbazian H, Mirza-Aghazadeh-Attari M, Borhani A, Mohseni A, Madani SP, Ansari G, Pawlik TM, Kamel IR. Multimodality imaging of hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J Surg Oncol 2023;128:519-530. [PMID: 37439096 DOI: 10.1002/jso.27396] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/26/2023] [Revised: 07/03/2023] [Accepted: 07/04/2023] [Indexed: 07/14/2023]

Bizeul J, Ronot M, Roux M, Cannella R, Lebigot J, Aubé C, Paisant A. Evaluation of washout using subtraction MRI for the diagnosis of hepatocellular carcinoma in cirrhotic patients with spontaneously T1-hyperintense nodules. Diagn Interv Imaging 2023;104:427-434. [PMID: 37120391 DOI: 10.1016/j.diii.2023.04.005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/15/2023] [Revised: 04/04/2023] [Accepted: 04/12/2023] [Indexed: 05/01/2023]

Abstract

PURPOSE

The purpose of this study was to assess the value of subtraction imaging on post-arterial phase images (i.e., portal venous, delayed/transitional and hepatobiliary phases) for the non-invasive diagnosis of hepatocellular carcinoma (HCC) in spontaneously hyperintense nodules on T1-weighted imaging in patients with cirrhosis.

MATERIALS AND METHODS

Forty-five patients with a total 55 hepatic nodules that were spontaneously hyperintense on T1-weighted images were initially retrieved. All patients underwent MRI examination of the liver using extracellular agent. Each nodule was assessed for sensitivity and specificity using LI-RADS (Liver Imaging Reporting and Data System) during two reading sessions performed first without then with subtraction images on post-arterial phase images. The final standard of reference was defined by a step-by-step algorithm previously published combining histology, typical imaging, alfa fetoprotein and follow-up.

RESULTS

Forty-six nodules (26 HCC) in 39 patients with cirrhosis were analyzed. Using LI-RADS, the sensitivity and specificity for the diagnosis of HCC were 64% (95% CI: 41-83) and 67% (95% CI: 41-87) without subtraction; and 73% (95% CI: 50-89) (P > 0.999) and 33% (95% CI: 13-59) (P = 0.553) on subtraction imaging using extracellular contrast agent. Fifty-five percent (22/40) of nodules displayed a washout without subtraction and 70% (28/40) did so on subtraction imaging obtained with extracellular contrast agent. Twenty nodules out of 40 (50%) were classified LI-RADS 5 without subtraction, and 28 out of 40 nodules (70%) with subtraction.

CONCLUSION

The results of this study suggest that the use of subtraction imaging on post-arterial phase images (i.e., PVP, DP/TP and HBP) is not relevant for the non-invasive diagnosis of HCC for spontaneously hyperintense nodules on T1-weighted images in patients with liver cirrhosis.

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Pan J, Song M, Yang L, Zhao Y, Zhu Y, Wang M, Chen F. The role of enhancing capsule and modified capsule appearances in LI-RADS for diagnosing HCC ≤ 3.0 cm on gadoxetate disodium-enhanced MRI. Eur Radiol 2023;33:5801-5811. [PMID: 36894754 DOI: 10.1007/s00330-023-09487-2] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/19/2022] [Revised: 01/30/2023] [Accepted: 02/06/2023] [Indexed: 03/11/2023]

Abstract

OBJECTIVES

To evaluate the value of using enhancing capsule (EC) or modified capsule appearance as a major feature in LI-RADS for diagnosing HCC ≤ 3.0 cm on gadoxetate disodium-enhanced MRI (Gd-EOB-MRI), and to explore the relationship between the imaging features and the histological fibrous capsule.

METHODS

This retrospective study enrolled 342 hepatic lesions ≤ 3.0 cm in 319 patients that underwent Gd-EOB-MRIs from January 2018 to March 2021. During dynamic phases and hepatobiliary phase, the modified capsule appearance added the nonenhancing capsule (NEC) (modified LI-RADS + NEC) or corona enhancement (CoE) (modified LI-RADS + CoE) to EC as an alternative capsule appearance. Inter-reader agreement of imaging features was assessed. The diagnostic performances of LI-RADS, LI-RADS with EC ignored, and two modified LI-RADS were compared, followed by Bonferroni correction. Multivariable regression analysis was performed to identify the independent features associated with the histological fibrous capsule.

RESULTS

The inter-reader agreement on EC (0.64) was lower than that on the NEC alternative (0.71) but better than that on CoE alternative (0.58). For HCC diagnosis, compared to LI-RADS, LI-RADS with EC ignored showed significantly lower sensitivity (72.7% vs. 67.4%, p < 0.001) with comparable specificity (89.3% vs. 90.7%, p = 1.000). Two modified LI-RADS showed slightly higher sensitivity and lower specificity than LI-RADS, without statistical significance (all p ≥ 0.006). The AUC was highest with modified LI-RADS + NEC (0.82). Both EC and NEC were significantly associated with the fibrous capsule (p < 0.05).

CONCLUSION

EC appearance improved the diagnostic sensitivity of LI-RADS for HCC ≤ 3.0 cm on Gd-EOB-MRI. Considering NEC as an alternative capsule appearance allowed for better inter-reader reliability and comparable diagnostic ability.

KEY POINTS

• Using the enhancing capsule as a major feature in LI-RADS significantly improved the sensitivity of diagnosing HCC ≤ 3.0 cm without reducing specificity on gadoxetate disodium-enhanced MRI. • Compared to the corona enhancement, the nonenhancing capsule might be a preferable alternative capsule appearance for diagnosing HCC ≤ 3.0 cm. • Capsule appearance should be considered a major feature in LI-RADS for diagnosing HCC ≤ 3.0 cm, regardless whether the capsule appears to be enhancing or nonenhancing.

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Rich NE, Chernyak V. Standardizing liver imaging reporting and interpretation: LI-RADS and beyond. Hepatol Commun 2023;7:e00186. [PMID: 37314738 PMCID: PMC10270536 DOI: 10.1097/hc9.0000000000000186] [Citation(s) in RCA: 4] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/03/2023] [Accepted: 05/02/2023] [Indexed: 06/15/2023] Open

Nishioka E, Sofue K, Maruyama K, Ueshima E, Ueno Y, Tsurusaki M, Komatsu S, Fukumoto T, Murakami T. Improved diagnosis of histological capsule in hepatocallular carcinoma by using nonenhancing capsule appearance in addition to enhancing capsule appearance in gadoxetic acid-enhanced MRI. Sci Rep 2023;13:6113. [PMID: 37059750 PMCID: PMC10104865 DOI: 10.1038/s41598-023-33048-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/10/2022] [Accepted: 04/06/2023] [Indexed: 04/16/2023] Open

Malviya KK, Verma A. Importance of Anatomical Variation of the Hepatic Artery for Complicated Liver and Pancreatic Surgeries: A Review Emphasizing Origin and Branching. Diagnostics (Basel) 2023;13:diagnostics13071233. [PMID: 37046451 PMCID: PMC10093498 DOI: 10.3390/diagnostics13071233] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/31/2023] [Revised: 03/21/2023] [Accepted: 03/22/2023] [Indexed: 04/14/2023] Open

An Overview of Hepatocellular Carcinoma Surveillance Focusing on Non-Cirrhotic NAFLD Patients: A Challenge for Physicians. Biomedicines 2023;11:biomedicines11020586. [PMID: 36831120 PMCID: PMC9953185 DOI: 10.3390/biomedicines11020586] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/14/2023] [Revised: 02/08/2023] [Accepted: 02/09/2023] [Indexed: 02/18/2023] Open

Utility of PET Scans in the Diagnosis and Management of Gastrointestinal Tumors. Dig Dis Sci 2022;67:4633-4653. [PMID: 35908126 DOI: 10.1007/s10620-022-07616-3] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Accepted: 05/27/2022] [Indexed: 12/14/2022]

Chartampilas E, Rafailidis V, Georgopoulou V, Kalarakis G, Hatzidakis A, Prassopoulos P. Current Imaging Diagnosis of Hepatocellular Carcinoma. Cancers (Basel) 2022;14:cancers14163997. [PMID: 36010991 PMCID: PMC9406360 DOI: 10.3390/cancers14163997] [Citation(s) in RCA: 15] [Impact Index Per Article: 5.0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/09/2022] [Revised: 08/10/2022] [Accepted: 08/15/2022] [Indexed: 11/23/2022] Open

Abstract

Simple Summary

The role of imaging in the management of hepatocellular carcinoma (HCC) has significantly evolved and expanded beyond the plain radiological confirmation of the tumor based on the typical appearance in a multiphase contrast-enhanced CT or MRI examination. The introduction of hepatobiliary contrast agents has enabled the diagnosis of hepatocarcinogenesis at earlier stages, while the application of ultrasound contrast agents has drastically upgraded the role of ultrasound in the diagnostic algorithms. Newer quantitative techniques assessing blood perfusion on CT and MRI not only allow earlier diagnosis and confident differentiation from other lesions, but they also provide biomarkers for the evaluation of treatment response. As distinct HCC subtypes are identified, their correlation with specific imaging features holds great promise for estimating tumor aggressiveness and prognosis. This review presents the current role of imaging and underlines its critical role in the successful management of patients with HCC.

Abstract

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer related death worldwide. Radiology has traditionally played a central role in HCC management, ranging from screening of high-risk patients to non-invasive diagnosis, as well as the evaluation of treatment response and post-treatment follow-up. From liver ultrasonography with or without contrast to dynamic multiple phased CT and dynamic MRI with diffusion protocols, great progress has been achieved in the last decade. Throughout the last few years, pathological, biological, genetic, and immune-chemical analyses have revealed several tumoral subtypes with diverse biological behavior, highlighting the need for the re-evaluation of established radiological methods. Considering these changes, novel methods that provide functional and quantitative parameters in addition to morphological information are increasingly incorporated into modern diagnostic protocols for HCC. In this way, differential diagnosis became even more challenging throughout the last few years. Use of liver specific contrast agents, as well as CT/MRI perfusion techniques, seem to not only allow earlier detection and more accurate characterization of HCC lesions, but also make it possible to predict response to treatment and survival. Nevertheless, several limitations and technical considerations still exist. This review will describe and discuss all these imaging modalities and their advances in the imaging of HCC lesions in cirrhotic and non-cirrhotic livers. Sensitivity and specificity rates, method limitations, and technical considerations will be discussed.

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Vidili G, Arru M, Solinas G, Calvisi DF, Meloni P, Sauchella A, Turilli D, Fabio C, Cossu A, Madeddu G, Babudieri S, Zocco MA, Iannetti G, Di Lembo E, Delitala AP, Manetti R. Contrast-enhanced ultrasound Liver Imaging Reporting and Data System: Lights and shadows in hepatocellular carcinoma and cholangiocellular carcinoma diagnosis. World J Gastroenterol 2022;28:3488-3502. [PMID: 36158272 PMCID: PMC9346460 DOI: 10.3748/wjg.v28.i27.3488] [Citation(s) in RCA: 18] [Impact Index Per Article: 6.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/17/2021] [Revised: 02/10/2022] [Accepted: 06/16/2022] [Indexed: 02/06/2023] Open

Abstract

BACKGROUND

Contrast-enhanced ultrasound (CEUS) is considered a secondary examination compared to computed tomography (CT) and magnetic resonance imaging (MRI) in the diagnosis of hepatocellular carcinoma (HCC), due to the risk of misdiagnosing intrahepatic cholangiocarcinoma (ICC). The introduction of CEUS Liver Imaging Reporting and Data System (CEUS LI-RADS) might overcome this limitation. Even though data from the literature seems promising, its reliability in real-life context has not been well-established yet.

AIM

To test the accuracy of CEUS LI-RADS for correctly diagnosing HCC and ICC in cirrhosis.

METHODS

CEUS LI-RADS class was retrospectively assigned to 511 nodules identified in 269 patients suffering from liver cirrhosis. The diagnostic standard for all nodules was either biopsy (102 nodules) or CT/MRI (409 nodules). Common diagnostic accuracy indexes such as sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were assessed for the following associations: CEUS LR-5 and HCC; CEUS LR-4 and 5 merged class and HCC; CEUS LR-M and ICC; and CEUS LR-3 and malignancy. The frequency of malignant lesions in CEUS LR-3 subgroups with different CEUS patterns was also determined. Inter-rater agreement for CEUS LI-RADS class assignment and for major CEUS pattern identification was evaluated.

RESULTS

CEUS LR-5 predicted HCC with a 67.6% sensitivity, 97.7% specificity, and 99.3% PPV (P < 0.001). The merging of LR-4 and 5 offered an improved 93.9% sensitivity in HCC diagnosis with a 94.3% specificity and 98.8% PPV (P < 0.001). CEUS LR-M predicted ICC with a 91.3% sensitivity, 96.7% specificity, and 99.6% NPV (P < 0.001). CEUS LR-3 predominantly included benign lesions (only 28.8% of malignancies). In this class, the hypo-hypo pattern showed a much higher rate of malignant lesions (73.3%) than the iso-iso pattern (2.6%). Inter-rater agreement between internal raters for CEUS-LR class assignment was almost perfect (n = 511, k = 0.94, P < 0.001), while the agreement among raters from separate centres was substantial (n = 50, k = 0.67, P < 0.001). Agreement was stronger for arterial phase hyperenhancement (internal k = 0.86, P < 2.7 × 10-214; external k = 0.8, P < 0.001) than washout (internal k = 0.79, P < 1.6 × 10-202; external k = 0.71, P < 0.001).

CONCLUSION

CEUS LI-RADS is effective but can be improved by merging LR-4 and 5 to diagnose HCC and by splitting LR-3 into two subgroups to differentiate iso-iso nodules from other patterns.

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Affiliation(s)

Gianpaolo Vidili Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Marco Arru Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Giuliana Solinas Department of Biomedical Sciences, Public Health-Laboratory of Biostatistics, University of Sassari, Sassari 07100, Italy
Diego Francesco Calvisi Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Pierluigi Meloni Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Assunta Sauchella Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Davide Turilli Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Claudio Fabio Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Antonio Cossu Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Giordano Madeddu Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Sergio Babudieri Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Maria Assunta Zocco Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University, Rome 00168, Italy
Giovanni Iannetti Ultrasound Unit, Ospedale S. Spirito, Pescara 65123, Italy
Enza Di Lembo Ultrasound Unit, Ospedale S. Spirito, Pescara 65123, Italy
Alessandro Palmerio Delitala Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy
Roberto Manetti Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari 07100, Italy

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Wei MC, Zhang YJ, Chen MS, Chen Y, Lau WY, Peng ZW. Adjuvant Sorafenib Following Radiofrequency Ablation for Early-Stage Recurrent Hepatocellular Carcinoma With Microvascular Invasion at the Initial Hepatectomy. Front Oncol 2022;12:868429. [PMID: 35814378 PMCID: PMC9260661 DOI: 10.3389/fonc.2022.868429] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/02/2022] [Accepted: 05/23/2022] [Indexed: 01/27/2023] Open

Abstract

Background

The efficacy of radiofrequency ablation (RFA) for patients with early-stage recurrent hepatocellular carcinoma (HCC) with microvascular invasion (MVI) at the initial hepatectomy is limited. Our study aimed to explore whether adjuvant sorafenib following RFA could improve the situation.

Methods

We retrospectively included 211 patients with early-stage (tumor number of ≤3 and tumor size of 2–5 cm) recurrent HCC with MVI at the initial hepatectomy who underwent adjuvant sorafenib following RFA or RFA alone in 13 centers from June 2013 to June 2020. In the combination group, sorafenib of 400 mg twice daily was administered within 7 days after RFA. Overall survival (OS) and recurrence-free survival (RFS) were compared. Subgroup analysis based on MVI grade was performed. MVI grade was based on the practice guidelines for the pathological diagnosis of HCC and included M1 (≤5 MVI sites, all located within adjacent peritumoral liver tissues 0–1 cm away from the tumor margin) and M2 (>5 MVI sites, or any MVI site located within adjacent peritumoral liver tissues > 1 cm away from the tumor margin).

Results

A total of 103 patients received the combination therapy and 108 patients received RFA alone. The combination therapy provided better survival than RFA alone (median RFS: 17.7 vs. 13.1 months, P < 0.001; median OS: 32.0 vs. 25.0 months, P = 0.002). Multivariable analysis revealed that treatment allocation was an independent prognostic factor. On subgroup analysis, the combination therapy provided better survival than RFA alone in patients with M1 along with either a tumor size of 3–5 cm, tumor number of two to three, or alpha-fetoprotein (AFP) > 400 μg/L, and in those with M2 along with either a tumor size of 2–3 cm, one recurrent tumor, or AFP ≤ 400 μg/L.

Conclusions

Adjuvant sorafenib following RFA was associated with better survival than RFA alone in patients with early-stage recurrent HCC with MVI at the initial hepatectomy. Moreover, MVI grade could guide the application of adjuvant sorafenib.

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Nadarevic T, Colli A, Giljaca V, Fraquelli M, Casazza G, Manzotti C, Štimac D, Miletic D. Magnetic resonance imaging for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease. Cochrane Database Syst Rev 2022;5:CD014798. [PMID: 35521901 PMCID: PMC9074390 DOI: 10.1002/14651858.cd014798.pub2] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/12/2022]

Abstract

BACKGROUND

Hepatocellular carcinoma occurs mostly in people with chronic liver disease and ranks sixth in terms of global incidence of cancer, and third in terms of cancer deaths. In clinical practice, magnetic resonance imaging (MRI) is used as a second-line diagnostic imaging modality to confirm the presence of focal liver lesions suspected as hepatocellular carcinoma on prior diagnostic test such as abdominal ultrasound or alpha-fetoprotein, or both, either in surveillance programmes or in clinical settings. According to current guidelines, a single contrast-enhanced imaging study (computed tomography (CT) or MRI) showing typical hallmarks of hepatocellular carcinoma in people with cirrhosis is considered valid to diagnose hepatocellular carcinoma. The detection of hepatocellular carcinoma amenable to surgical resection could improve the prognosis. However, a significant number of hepatocellular carcinomas do not show typical hallmarks on imaging modalities, and hepatocellular carcinoma may, therefore, be missed. There is no clear evidence of the benefit of surveillance programmes in terms of overall survival: the conflicting results can be a consequence of inaccurate detection, ineffective treatment, or both. Assessing the diagnostic accuracy of MRI may clarify whether the absence of benefit could be related to underdiagnosis. Furthermore, an assessment of the accuracy of MRI in people with chronic liver disease who are not included in surveillance programmes is needed for either ruling out or diagnosing hepatocellular carcinoma.

OBJECTIVES

Primary: to assess the diagnostic accuracy of MRI for the diagnosis of hepatocellular carcinoma of any size and at any stage in adults with chronic liver disease. Secondary: to assess the diagnostic accuracy of MRI for the diagnosis of resectable hepatocellular carcinoma in adults with chronic liver disease, and to identify potential sources of heterogeneity in the results.

SEARCH METHODS

We searched the Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Hepato-Biliary Group Diagnostic Test of Accuracy Studies Register, the Cochrane Library, MEDLINE, Embase, and three other databases to 9 November 2021. We manually searched articles retrieved, contacted experts, handsearched abstract books from meetings held during the last 10 years, and searched for literature in OpenGrey (9 November 2021). Further information was requested by e-mails, but no additional information was provided. No data was obtained through correspondence with investigators. We applied no language or document-type restrictions.

SELECTION CRITERIA

Studies assessing the diagnostic accuracy of MRI for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease, with cross-sectional designs, using one of the acceptable reference standards, such as pathology of the explanted liver and histology of resected or biopsied focal liver lesion with at least a six-month follow-up.

DATA COLLECTION AND ANALYSIS

At least two review authors independently screened studies, extracted data, and assessed the risk of bias and applicability concerns, using the QUADAS-2 checklist. We presented the results of sensitivity and specificity, using paired forest plots, and we tabulated the results. We used a hierarchical meta-analysis model where appropriate. We presented uncertainty of the accuracy estimates using 95% confidence intervals (CIs). We double-checked all data extractions and analyses.

MAIN RESULTS

We included 34 studies, with 4841 participants. We judged all studies to be at high risk of bias in at least one domain because most studies used different reference standards, often inappropriate to exclude the presence of the target condition, and the time interval between the index test and the reference standard was rarely defined. Regarding applicability, we judged 15% (5/34) of studies to be at low concern and 85% (29/34) of studies to be at high concern mostly owing to characteristics of the participants, most of whom were on waiting lists for orthotopic liver transplantation, and due to pathology of the explanted liver being the only reference standard. MRI for hepatocellular carcinoma of any size and stage: sensitivity 84.4% (95% CI 80.1% to 87.9%) and specificity 93.8% (95% CI 90.1% to 96.1%) (34 studies, 4841 participants; low-certainty evidence). MRI for resectable hepatocellular carcinoma: sensitivity 84.3% (95% CI 77.6% to 89.3%) and specificity 92.9% (95% CI 88.3% to 95.9%) (16 studies, 2150 participants; low-certainty evidence). The observed heterogeneity in the results remains mostly unexplained. The sensitivity analyses, which included only studies with clearly prespecified positivity criteria and only studies in which the reference standard results were interpreted without knowledge of the results of the index test, showed no variation in the results.

AUTHORS' CONCLUSIONS

We found that using MRI as a second-line imaging modality to diagnose hepatocellular carcinoma of any size and stage, 16% of people with hepatocellular carcinoma would be missed, and 6% of people without hepatocellular carcinoma would be unnecessarily treated. For resectable hepatocellular carcinoma, we found that 16% of people with resectable hepatocellular carcinoma would improperly not be resected, while 7% of people without hepatocellular carcinoma would undergo inappropriate surgery. The uncertainty resulting from the high risk of bias in the included studies and concerns regarding their applicability limit our ability to confidently draw conclusions based on our results.

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Li X, Yao Q, Liu C, Wang J, Zhang H, Li S, Cai P. Macrotrabecular-Massive Hepatocellular Carcinoma: What Should We Know? J Hepatocell Carcinoma 2022;9:379-387. [PMID: 35547829 PMCID: PMC9084381 DOI: 10.2147/jhc.s364742] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/05/2022] [Accepted: 04/23/2022] [Indexed: 12/11/2022] Open

Bartolotta TV, Randazzo A, Bruno E, Taibbi A. Focal liver lesions in cirrhosis: Role of contrast-enhanced ultrasonography. World J Radiol 2022;14:70-81. [PMID: 35646291 PMCID: PMC9124982 DOI: 10.4329/wjr.v14.i4.70] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/25/2021] [Revised: 05/16/2021] [Accepted: 04/08/2022] [Indexed: 02/06/2023] Open

Liver imaging: it is time to adopt standardized terminology. Eur Radiol 2022;32:6291-6301. [PMID: 35389052 DOI: 10.1007/s00330-022-08769-5] [Citation(s) in RCA: 12] [Impact Index Per Article: 4.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/16/2022] [Revised: 03/18/2022] [Accepted: 03/22/2022] [Indexed: 12/28/2022]

Xie S, Zhang Y, Chen J, Jiang T, Liu W, Rong D, Sun L, Zhang L, He B, Wang J. Can modified LI-RADS increase the sensitivity of LI-RADS v2018 for the diagnosis of 10-19 mm hepatocellular carcinoma on gadoxetic acid-enhanced MRI? Abdom Radiol (NY) 2022;47:596-607. [PMID: 34773467 DOI: 10.1007/s00261-021-03339-7] [Citation(s) in RCA: 13] [Impact Index Per Article: 4.3] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/03/2021] [Revised: 10/29/2021] [Accepted: 10/29/2021] [Indexed: 12/11/2022]

Liver Imaging Reporting and Data System: Review of Pros and Cons. Semin Liver Dis 2022;42:104-111. [PMID: 34298576 DOI: 10.1055/s-0041-1732356] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/01/2023]

van der Pol CB, McInnes MDF, Salameh JP, Levis B, Chernyak V, Sirlin CB, Bashir MR, Allen BC, Burke LMB, Choi JY, Choi SH, Forner A, Fraum TJ, Giamperoli A, Jiang H, Joo I, Kang Z, Kierans AS, Kang HJ, Khatri G, Kim JH, Kim MJ, Kim SY, Kim YY, Kwon H, Lee JM, Lewis SC, McGinty KA, Mulazzani L, Park MS, Piscaglia F, Podgórska J, Reiner CS, Ronot M, Rosiak G, Song B, Song JS, Tang A, Terzi E, Wang J, Wang W, Wilson SR, Yokoo T. CT/MRI and CEUS LI-RADS Major Features Association with Hepatocellular Carcinoma: Individual Patient Data Meta-Analysis. Radiology 2022;302:326-335. [PMID: 34783596 DOI: 10.1148/radiol.2021211244] [Citation(s) in RCA: 51] [Impact Index Per Article: 17.0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/14/2022]

Abstract

Background The Liver Imaging Reporting and Data System (LI-RADS) assigns a risk category for hepatocellular carcinoma (HCC) to imaging observations. Establishing the contributions of major features can inform the diagnostic algorithm. Purpose To perform a systematic review and individual patient data meta-analysis to establish the probability of HCC for each LI-RADS major feature using CT/MRI and contrast-enhanced US (CEUS) LI-RADS in patients at high risk for HCC. Materials and Methods Multiple databases (MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Scopus) were searched for studies from January 2014 to September 2019 that evaluated the accuracy of CT, MRI, and CEUS for HCC detection using LI-RADS (CT/MRI LI-RADS, versions 2014, 2017, and 2018; CEUS LI-RADS, versions 2016 and 2017). Data were centralized. Clustering was addressed at the study and patient levels using mixed models. Adjusted odds ratios (ORs) with 95% CIs were determined for each major feature using multivariable stepwise logistic regression. Risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) (PROSPERO protocol: CRD42020164486). Results A total of 32 studies were included, with 1170 CT observations, 3341 MRI observations, and 853 CEUS observations. At multivariable analysis of CT/MRI LI-RADS, all major features were associated with HCC, except threshold growth (OR, 1.6; 95% CI: 0.7, 3.6; P = .07). Nonperipheral washout (OR, 13.2; 95% CI: 9.0, 19.2; P = .01) and nonrim arterial phase hyperenhancement (APHE) (OR, 10.3; 95% CI: 6.7, 15.6; P = .01) had stronger associations with HCC than enhancing capsule (OR, 2.4; 95% CI: 1.7, 3.5; P = .03). On CEUS images, APHE (OR, 7.3; 95% CI: 4.6, 11.5; P = .01), late and mild washout (OR, 4.1; 95% CI: 2.6, 6.6; P = .01), and size of at least 20 mm (OR, 1.6; 95% CI: 1.04, 2.5; P = .04) were associated with HCC. Twenty-five studies (78%) had high risk of bias due to reporting ambiguity or study design flaws. Conclusion Most Liver Imaging Reporting and Data System major features had different independent associations with hepatocellular carcinoma; for CT/MRI, arterial phase hyperenhancement and washout had the strongest associations, whereas threshold growth had no association. © RSNA, 2021 Online supplemental material is available for this article.

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Affiliation(s)

Christian B van der Pol From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Matthew D F McInnes From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Jean-Paul Salameh From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Brooke Levis From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Victoria Chernyak From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Claude B Sirlin From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Mustafa R Bashir From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Brian C Allen From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Lauren M B Burke From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Jin-Young Choi From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Sang Hyun Choi From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Alejandro Forner From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Tyler J Fraum From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Alice Giamperoli From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Hanyu Jiang From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Ijin Joo From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Zhen Kang From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Andrea S Kierans From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Hyo-Jin Kang From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Gaurav Khatri From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Jung Hoon Kim From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Myeong-Jin Kim From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
So Yeon Kim From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Yeun-Yoon Kim From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Heejin Kwon From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Jeong Min Lee From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Sara C Lewis From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Katrina A McGinty From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Lorenzo Mulazzani From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Mi-Suk Park From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Fabio Piscaglia From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Joanna Podgórska From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Caecilia S Reiner From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Maxime Ronot From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Grzegorz Rosiak From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Bin Song From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Ji Soo Song From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
An Tang From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Eleonora Terzi From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Jin Wang From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Wei Wang From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Stephanie R Wilson From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)
Takeshi Yokoo From the Dept of Diagnostic Imaging, Juravinski Hosp and Cancer Centre, Hamilton Health Sciences, McMaster Univ, Hamilton, Canada (C.B.v.d.P.); Dept of Radiology and Epidemiology, Univ of Ottawa, Ottawa, Canada (M.D.F.M.); Ottawa Hosp Research Inst Clinical Epidemiology Program, Dept of Medical Imaging, the Ottawa Hosp-Civic Campus, 1053 Carling Ave, Room c-159, Ottawa, ON, Canada K1E 4Y9 (M.D.F.M.); Faculty of Health Sciences, Queen's Univ, Kingston, Canada (J.P.S.); Clinical Epidemiology Program, Ottawa Hosp Research Inst, Ottawa, Canada (J.P.S.); Centre for Prognosis Research, School of Medicine, Keele Univ, Staffordshire, UK (B.L.); Dept of Radiology, Montefiore Medical Ctr, Bronx, NY (V.C.); Liver Imaging Group, Dept of Radiology, Univ of California San Diego, San Diego, Calif (C.B.S.); Depts of Radiology (M.R.B., B.C.A.) and Medicine (M.R.B.) and Ctr for Advanced Magnetic Resonance Development (M.R.B.), Duke Univ Medical Ctr, Durham, NC; Dept of Radiology, Univ of North Carolina, Chapel Hill, NC (M.R.B., L.M.B.B., K.A.M.); Dept of Radiology, Research Inst of Radiological Science, Yonsei Univ College of Medicine, Seoul, Korea (J.Y.C., M.J.K., Y.Y.K., M.S.P.); Asan Medical Ctr, Univ of Ulsan College of Medicine, Seoul, Korea (S.H.C.); BCLC Group, Liver Unit, Hosp Clínic of Barcelona, Barcelona, Spain (A.F.); IDIBAPS, CIBERehd, Univ of Barcelona, Barcelona, Spain (A.F.); Mallinckrodt Inst of Radiology, Washington Univ School of Medicine, St Louis, Mo (T.J.F.); Div of Internal Medicine, Hepatobiliary and Immunoallergic Diseases (A.G., F.P., E.T.), and Emergency Dept, Medicina d'Urgenza e Pronto Soccorso (L.M.), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (H.J.); Dept of Radiology (I.J., H.J.K., J.H.K., J.M.L.) and Inst of Radiation Medicine (J.H.K., J.M.L.), Seoul National Univ Hosp, Seoul, Korea; Dept of Radiology, Seoul National Univ College of Medicine, Seoul, Korea (I.J., J.H.K., J.M.L.); Dept of Radiology, Tongji Hosp, Tongji Medical College, Wuhan, China (Z.K.); Huazhong Univ of Science and Technology, Wuhan, China (Z.K.); Dept of Radiology, Weill Cornell Medical Ctr, New York, NY (A.S.K.); Dept of Radiology (G.K., T.Y.) and Advanced Imaging Research Ctr (T.Y.), Univ of Texas Southwestern Medical Ctr, Dallas, Tex; Dept of Radiology and Research Inst of Radiology, Univ of Ulsan College of Medicine, Asan Medical Ctr, Seoul, Korea (S.Y.K.); Dept of Radiology, Dong-A Univ Hosp, Dong-A Univ College of Medicine, Busan, Korea (H.K.); Dept of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.L.); 2nd Radiology Dept, Warsaw Medical Univ, Warsaw, Poland (J.P., G.R.); Inst of Diagnostic and Interventional Radiology, Univ Hosp Zurich, Zurich, Switzerland (C.S.R.); Dept of Radiology, Beaujon Hosp, APHP.Nord, Clichy, France (M.R.); Université de Paris, Paris, France (M.R.); Dept of Radiology, West China Hosp, Sichuan Univ, Chengdu, China (B.S.); Dept of Radiology, Jeonbuk National Univ Medical School and Hosp, Jeonju, Korea (J.S.S.); Dept of Radiology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada (A.T.); Dept of Radiology, the Third Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China (J.W.); Dept of Medical Ultrasonics, Inst of Diagnostic and Interventional Ultrasound, the First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China (W.W.); Depts of Radiology and Medicine, Div of Gastroenterology, Univ of Calgary, Calgary, Canada (S.R.W.); and Foothills Medical Centre, Calgary, Canada (S.R.W.)

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Min JH, Kim JM, Kim YK, Kim H, Cha DI, Kang TW, Choi GS, Choi SY, Ahn S. EASL versus LI-RADS: Intra-individual comparison of MRI with extracellular contrast and gadoxetic acid for diagnosis of small HCC. Liver Int 2021;41:2986-2996. [PMID: 34242468 DOI: 10.1111/liv.15012] [Citation(s) in RCA: 11] [Impact Index Per Article: 2.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/06/2021] [Revised: 06/15/2021] [Accepted: 07/05/2021] [Indexed: 12/13/2022]

Consul N, Sirlin CB, Chernyak V, Fetzer DT, Masch WR, Arora SS, Do RKG, Marks RM, Fowler KJ, Borhani AA, Elsayes KM. Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization. Radiographics 2021;41:1657-1675. [PMID: 34559586 DOI: 10.1148/rg.2021210019] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/31/2022]

Affiliation(s)

Nikita Consul From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Claude B Sirlin From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Victoria Chernyak From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
David T Fetzer From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
William R Masch From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Sandeep S Arora From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Richard K G Do From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Robert M Marks From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Kathryn J Fowler From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Amir A Borhani From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)
Khaled M Elsayes From the Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (N.C.); University of California San Diego Health, San Diego, Calif (C.B.S., K.J.F.); Montefiore Medical Center, Bronx, NY (V.C.); University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); University of Michigan Medical School, Ann Arbor, Mich (W.R.M.); Yale School of Medicine, New Haven, Conn (S.S.A.); Memorial Sloan Kettering Cancer Center, New York, NY (R.K.G.D.); Naval Medical Center San Diego, San Diego, Calif (R.M.M.); Northwestern University, Chicago, Ill (A.A.B.); and University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.)

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Hunold P, Bucher AM, Sandstede J, Janka R, Fritz LB, Regier M, Loose R, Barkhausen J, Mentzel HJ, Zimmer C, Antoch G. Statement of the German Roentgen Society, German Society of Neuroradiology, and Society of German-speaking Pediatric Radiologists on Requirements for the Performance and Reporting of MR Imaging Examinations Outside of Radiology. ROFO-FORTSCHR RONTG 2021;193:1050-1061. [PMID: 33831956 DOI: 10.1055/a-1463-3626] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/21/2022]

Abstract

BACKGROUND

Magnetic Resonance Imaging (MRI) is a very innovative, but at the same time complex and technically demanding diagnostic method in radiology. It plays an increasing role in high-quality and efficient patient management. Quality assurance in MRI is of utmost importance to avoid patient risks due to errors before and during the examination and when reporting the results. Therefore, MRI requires higher physician qualification and expertise than any other diagnostic imaging technique in medicine. This holds true for indication, performance of the examination itself, and in particular for image evaluation and writing of the report. In Germany, the radiologist is the only specialist who is systematically educated in all aspects of MRI during medical specialty training and who must document a specified, high number of examinations during this training. However, also non-radiologist physicians are increasingly endeavoring to conduct and bill MRI examinations on their own.

METHOD

In this position statement, the following aspects of quality assurance for MRI examinations and billing by radiologists and non-radiologist physician specialists are examined scientifically: Requirements for specialist physician training, MRI risks and contraindications, radiation protection in the case of non-ionizing radiation, application of MR contrast agents, requirements regarding image quality, significance of image artifacts and incidental findings, image evaluation and reporting, interdisciplinary communication and multiple-eyes principle, and impact on healthcare system costs.

CONCLUSION

The German Roentgen Society, German Society of Neuroradiology, and Society of German-speaking Pediatric Radiologists are critical with regard to MRI performance by non-radiologists in the interest of quality standards, patient welfare, and healthcare payers. The 24-month additional qualification in MRI as defined by the physician specialization regulations (Weiterbildungsordnung) through the German state medical associations (Landesärztekammern) is the only competence-based and quality-assured training program for board-certified specialist physicians outside radiology. This has to be required as the minimum standard for performance and reporting of MRI exams. Exclusively unstructured MRI training outside the physician specialization regulations has to be strictly rejected for reasons of patient safety. The performance and reporting of MRI examinations must be reserved for adequately trained and continuously educated specialist physicians.

KEY POINTS

· MR imaging plays an increasing role due to its high diagnostic value and serves as the reference standard in many indications.. · MRI is a complex technique that implies patient risks in case of inappropriare application or lack of expertise.. · In Germany, the radiologist is the only specialist physician that has been systematically trained in all aspects of MRI such as indication, performance, and reporting of examinations in specified, high numbers.. · The only competence-based and quality-assured MRI training program for specialist physicians outside radiology is the 24-month additional qualification as defined by the regulations through the German state medical associations.. · In view of quality-assurance and patient safety, a finalized training program following the physician specialization regulations has to be required for the performance and reporting of MRI examinations..

CITATION FORMAT

· Hunold P, Bucher AM, Sandstede J et al. Statement of the German Roentgen Society, German Society of Neuroradiology, and Society of German-speaking Pediatric Radiologists on Requirements for the Performance and Reporting of MR Imaging Examinations Outside of Radiology. Fortschr Röntgenstr 2021; 193: 1050 - 1060.

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Min JH, Kim JM, Kim YK, Kim H, Choi GS, Kang TW, Cha D, Hwang JA, Ko SE, Ahn S. A modified LI-RADS: targetoid tumors with enhancing capsule can be diagnosed as HCC instead of LR-M lesions. Eur Radiol 2021;32:912-922. [PMID: 34345947 DOI: 10.1007/s00330-021-08124-0] [Citation(s) in RCA: 6] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/15/2020] [Revised: 11/12/2020] [Accepted: 06/07/2021] [Indexed: 10/20/2022]

Abstract

OBJECTIVE

To elucidate whether the presence of enhancing capsule can be applied to establish a modified Liver Imaging Reporting and Data System (LI-RADS) to differentiate hepatocellular carcinoma (HCC) from non-HCC malignancies in extracellular contrast agent (ECA)-enhanced and hepatobiliary agent (HBA)-enhanced MRI.

METHODS

We enrolled 198 participants (161 men; mean age, 56.3 years) with chronic liver disease who underwent ECA-MRI and HBA-MRI before surgery for de novo hepatic nodule(s). Two reviewers assigned LI-RADS categories (v2018). We defined a "modified LR-5 category, which emphasizes enhancing capsule (mLR-5C)" over targetoid features and classifies tumors with both targetoid appearance and enhancing capsule as HCC instead of LR-M. We compared the diagnostic performance of conventional LI-RADS and modified LI-RADS criteria for both MRIs.

RESULTS

A total of 258 hepatic nodules (194 HCCs, 43 benign lesions, and 21 non-HCC malignancies; median size, 19 mm) were analyzed. By conventional LI-RADS, 47 (18.2%) nodules (31 HCCs and 16 non-HCC malignancies) were categorized as LR-M. The mLR-5C criterion showed superior sensitivity (ECA-MRI, 76.6% vs. 67.0%; HBA-MRI, 60.4% vs. 56.3%; both p < 0.05) while maintaining high specificity (ECA-MRI, 93.8% vs. 98.4%; HBA-MRI, 95.3% vs. 98.4%; both p > 0.05) compared with the LR-5 criterion. Using the mLR-5C criterion, ECA-MRI exhibited higher sensitivity than HBA-MRI (76.6% vs. 60.4%, p < 0.001) and similar specificity (93.8% vs. 95.3%, p > 0.99).

CONCLUSION

Our modified LI-RADS achieved superior sensitivity for diagnosing HCC, without compromising specificity compared with LR-5. ECA-MRI showed higher sensitivity in diagnosing HCC than HBA-MRI by applying the mLR-5C for LR-M lesions.

KEY POINTS

• By conventional LI-RADS, 31 (16.0%) of 194 HCCs were categorized as LR-M. • Among 31 HCCs categorized as LR-M, 19 HCCs or 8 HCCs were recategorized as HCC on ECA-MRI or HBA-MRI, respectively, after applying the modified LR-5 category, which allocates targetoid lesions with enhancing capsule as mLR-5C instead of LR-M. • The mLR-5C showed superior sensitivity compared with the LR-5 in both MRIs (ECA-MRI, 76.6% vs. 67.0%; HBA-MRI, 60.4% vs. 56.3%, both p < 0.05), while maintaining high specificity (ECA-MRI, 93.8% vs. 98.4%; HBA-MRI, 95.3% vs. 98.4%; both p > 0.05).

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Zhu Y, Weng S, Li Y, Yan C, Ye R, Wen L, Zhou L, Gao L. A radiomics nomogram based on contrast-enhanced MRI for preoperative prediction of macrotrabecular-massive hepatocellular carcinoma. Abdom Radiol (NY) 2021;46:3139-3148. [PMID: 33641018 DOI: 10.1007/s00261-021-02989-x] [Citation(s) in RCA: 31] [Impact Index Per Article: 7.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/27/2020] [Revised: 01/22/2021] [Accepted: 02/09/2021] [Indexed: 02/07/2023]

Abstract

BACKGROUND

Macrotrabecular-massive hepatocellular carcinoma (MTM-HCC) represents an aggressive form of hepatocellular carcinoma and is associated with poor survival outcomes.

AIMS

This study aimed to develop a radiomics nomogram based on contrast-enhanced MRI for preoperative prediction of MTM-HCC.

METHODS

This study enrolled 88 patients with histologically confirmed HCC, including 32 MTM-HCCs and 56 Non-MTM-HCCs. The clinical and gadobenate dimeglumine (Gd)-enhanced MRI features were retrospectively reviewed by two abdominal radiologists. The regions of interest (ROIs) on the largest cross-sectional image and two adjacent images of the tumor, from which radiomics features were extracted via MaZda software and a radiomics score (Rad-score) was calculated via Python software. Combined with the Rad-score and independent imaging factors, a radiomics nomogram was constructed using R software. Nomogram performance was estimated with calibration curve.

RESULTS

A total of eleven top weighted radiomics features were selected among five sequences of MR images. There was a significant difference in Rad-score between MTM-HCC and non-MTM-HCC patients (P < 0.001), where patients with MTM-HCC generally had higher Rad-scores (absolute value). After multivariate analysis, radiomics score (OR = 7.794, P < 0.001) and intratumor fat (OR = 9.963, P = 0.014) were determined as independent predictors associated with MTM-HCC. The area under the receiver operating characteristic (ROC) curve of the selected model was 0.813 (95% CI 0.714-0.912) and the optimal cutoff value was 0.60. The nomogram showed overall satisfactory prediction performance (AUC = 0.785 [95% CI 0.684-0.886]).

CONCLUSIONS

A contrast-enhanced MRI-based radiomics nomogram may be useful for preoperative prediction of MTM-HCC in primary HCC patients, allowing opportunity to improve the treatment course and patient outcomes.

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Reig M, Forner A, Ávila MA, Ayuso C, Mínguez B, Varela M, Bilbao I, Bilbao JI, Burrel M, Bustamante J, Ferrer J, Gómez MÁ, Llovet JM, De la Mata M, Matilla A, Pardo F, Pastrana MA, Rodríguez-Perálvarez M, Tabernero J, Urbano J, Vera R, Sangro B, Bruix J. Diagnosis and treatment of hepatocellular carcinoma. Update of the consensus document of the AEEH, AEC, SEOM, SERAM, SERVEI, and SETH. Med Clin (Barc) 2021;156:463.e1-463.e30. [PMID: 33461840 DOI: 10.1016/j.medcli.2020.09.022] [Citation(s) in RCA: 20] [Impact Index Per Article: 5.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/20/2020] [Revised: 09/12/2020] [Accepted: 09/15/2020] [Indexed: 12/12/2022]

Affiliation(s)

María Reig Unidad de Oncología Hepática (Barcelona Clinic Liver Cancer), Servicio de Hepatología, Hospital Clínic, IDIBAPS, Universidad de Barcelona, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España
Alejandro Forner Unidad de Oncología Hepática (Barcelona Clinic Liver Cancer), Servicio de Hepatología, Hospital Clínic, IDIBAPS, Universidad de Barcelona, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España
Matías A Ávila Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Programa de Hepatología, Centro de Investigación Médica Aplicada, Universidad de Navarra-IDISNA, Pamplona, España
Carmen Ayuso Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Servicio de Radiodiagnóstico, Hospital Clínic Barcelona, IDIBAPS, Universidad de Barcelona, Barcelona, España
Beatriz Mínguez Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Servicio de Hepatología, Hospital Universitario Vall d́Hebron, Grupo de Investigación en Enfermedades Hepáticas (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universidad Autónoma de Barcelona. Barcelona, España
María Varela Sección de Hepatología, Servicio de Aparato Digestivo, Hospital Universitario Central de Asturias. Oviedo, España
Itxarone Bilbao Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Servicio de Cirugía Hepatobiliopancreática y Trasplantes Digestivos, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona. Barcelona, España
José Ignacio Bilbao Unidad de Radiología Vascular e Intervencionista, Departamento de Radiodiagnóstico, Clínica Universidad de Navarra, Pamplona, España
Marta Burrel Servicio de Radiodiagnóstico, Hospital Clínic Barcelona, IDIBAPS, Universidad de Barcelona, Barcelona, España
Javier Bustamante Servicio de Gastroenterología y Hepatología, Sección de Hepatología y Trasplante, Hospital Universitario de Cruces, Baracaldo, España
Joana Ferrer Unidad de Oncología Hepática (Barcelona Clinic Liver Cancer), Servicio de Cirugía Hepatobiliopancreática, Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, España
Miguel Ángel Gómez Unidad de Cirugía Hepatobiliopancreática y Trasplantes, Hospital Universitario Virgen del Rocío, Sevilla, España
Josep María Llovet Grupo de Investigación Traslacional en Oncología Hepática, Servicio de Hepatología, Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, España
Manuel De la Mata Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Unidad Clínica de Aparato Digestivo, Hospital Universitario Reina Sofía, Córdoba, España
Ana Matilla Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Sección de Hepatología, Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid, España
Fernando Pardo Servicio de Cirugía Hepatobiliopancreática y Trasplante, Clínica Universidad de Navarra, Pamplona, España
Miguel A Pastrana Servicio de Radiodiagnóstico, Hospital Universitario Puerta de Hierro, Universidad Autónoma de Madrid, Madrid, España
Manuel Rodríguez-Perálvarez Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Unidad Clínica de Aparato Digestivo, Hospital Universitario Reina Sofía, Córdoba, España
Josep Tabernero Servicio de Oncología Médica, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, España
José Urbano Unidad de Radiología Vascular e Intervencionista, Servicio de Radiodiagnóstico, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, España
Ruth Vera Servicio de Oncología Médica, Complejo hospitalario de Navarra, Navarrabiomed-IDISNA, Pamplona, España
Bruno Sangro Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España; Unidad de Hepatología y Área de Oncología HBP, Clínica Universidad de Navarra-IDISNA, Pamplona, España.
Jordi Bruix Unidad de Oncología Hepática (Barcelona Clinic Liver Cancer), Servicio de Hepatología, Hospital Clínic, IDIBAPS, Universidad de Barcelona, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España.

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Caraiani C, Boca B, Bura V, Sparchez Z, Dong Y, Dietrich C. CT/MRI LI-RADS v2018 vs. CEUS LI-RADS v2017-Can Things Be Put Together? BIOLOGY 2021;10:412. [PMID: 34066607 PMCID: PMC8148521 DOI: 10.3390/biology10050412] [Citation(s) in RCA: 13] [Impact Index Per Article: 3.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 03/22/2021] [Revised: 04/17/2021] [Accepted: 04/30/2021] [Indexed: 12/27/2022]

The role of lesion hypointensity on gadobenate dimeglumine-enhanced hepatobiliary phase MRI as an additional major imaging feature for HCC classification using LI-RADS v2018 criteria. Eur Radiol 2021;31:7715-7724. [PMID: 33782766 DOI: 10.1007/s00330-021-07807-y] [Citation(s) in RCA: 11] [Impact Index Per Article: 2.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/18/2020] [Revised: 01/14/2021] [Accepted: 02/17/2021] [Indexed: 10/21/2022]

Abstract

OBJECTIVES

To determine the value of lesion hypointensity in the hepatobiliary phase (HBP) on gadobenate dimeglumine-enhanced MRI as an additional major imaging feature for diagnosis of hepatocellular carcinoma (HCC) using LI-RADS v2018 criteria.

METHODS

Between March 2016 and August 2018, 235 patients with 250 hepatic nodules at high risk of HCC underwent gadobenate dimeglumine-enhanced MRI. Two radiologists independently evaluated the imaging features and classified the nodules based on LI-RADS v2018 criteria, and their consensus data were used to calculate the diagnostic performance of LI-RADS categories. Two modified LI-RADS definitions were as follows: (1) LI-RADS-m1: HBP hypointensity as an additional major feature; (2) LI-RADS-m2: HBP hypointensity as an alternative to "enhancing capsule" as an additional major feature. The diagnostic performance of LR-5 categories was compared using McNemar's test.

RESULTS

The sensitivity and specificity for LR-5 classification using original LI-RADS v2018 criteria were 78.1% and 96.3%, respectively. Significantly improved sensitivity (82.7%; p = 0.004) with unchanged specificity (96.3%; p = 1.00) was seen for LR-5 classification using LI-RADS-m1. Similar sensitivity and specificity (82.7% and 96.3%, respectively) were also seen using LI-RADS-m2. Significantly improved sensitivity (79.5% vs. 64.0%; p = 0.031) with unchanged specificity (96.2% vs. 96.2%, p = 1.00) was seen using both LI-RADS-m1 and LI-RADS-m2 compared to the original LI-RADS v2018 for 39 HCC nodules measuring 10-19 mm.

CONCLUSIONS

Lesion hypointensity on gadobenate dimeglumine-enhanced HBP MRI may improve sensitivity for LR-5 classification beyond that achievable using conventional LI-RADS v2018 criteria. Lesion hypointensity may prove a suitable alternative imaging feature to enhancing capsule for accurate LR-5 classification.

KEY POINTS

• Including lesion hypointensity in the HBP as an additional major feature improved sensitivity for LR-5 classification on gadobenate dimeglumine-enhanced MRI. • Lesion hypointensity in the HBP can replace "enhancing capsule" as an additional major feature for LR-5 classification without impairing specificity.

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Barat M, Nguyen TTL, Hollande C, Coty JB, Hoeffel C, Terris B, Dohan A, Mallet V, Pol S, Soyer P. LI-RADS v2018 major criteria: Do hepatocellular carcinomas in non-alcoholic steatohepatitis differ from those in virus-induced chronic liver disease on MRI? Eur J Radiol 2021;138:109651. [PMID: 33740627 DOI: 10.1016/j.ejrad.2021.109651] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/09/2021] [Revised: 03/05/2021] [Accepted: 03/09/2021] [Indexed: 02/07/2023]

Kim YY, Kim YK, Min JH, Cha DI, Kim JM, Choi GS, Ahn S. Intraindividual Comparison of Hepatocellular Carcinoma Washout between MRIs with Hepatobiliary and Extracellular Contrast Agents. Korean J Radiol 2021;22:725-734. [PMID: 33660458 PMCID: PMC8076831 DOI: 10.3348/kjr.2020.1143] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/24/2020] [Revised: 11/06/2020] [Accepted: 12/15/2020] [Indexed: 11/15/2022] Open

Abstract

Objective

To intraindividually compare hepatocellular carcinoma (HCC) washout between MRIs using hepatobiliary agent (HBA) and extracellular agent (ECA).

Materials and Methods

This study included 114 prospectively enrolled patients with chronic liver disease (mean age, 55 ± 9 years; 94 men) who underwent both HBA-MRI and ECA-MRI before surgical resection for HCC between November 2016 and May 2019. For 114 HCCs, the lesion-to-liver visual signal intensity ratio (SIR) using a 5-point scale (−2 to +2) was evaluated in each phase. Washout was defined as negative visual SIR with temporal reduction of visual SIR from the arterial phase. Illusional washout (IW) was defined as a visual SIR of 0 with an enhancing capsule. The frequency of washout and MRI sensitivity for HCC using LR-5 or its modifications were compared between HBA-MRI and ECA-MRI. Subgroup analysis was performed according to lesion size (< 20 mm or ≥ 20 mm).

Results

The frequency of portal venous phase (PP) washout with HBA-MRI was comparable to that of delayed phase (DP) washout with ECA-MRI (77.2% [88/114] vs. 68.4% [78/114]; p = 0.134). The frequencies were also comparable when IW was allowed (79.8% [91/114] for HBA-MRI vs. 81.6% [93/114] for ECA-MRI; p = 0.845). The sensitivities for HCC of LR-5 (using PP or DP washout) were comparable between HBA-MRI and ECA-MRI (78.1% [89/114] vs. 73.7% [84/114]; p = 0.458). In HCCs < 20 mm, the sensitivity of LR-5 was higher on HBA-MRI than on ECA-MRI (70.8% [34/48] vs. 50.0% [24/48]; p = 0.034). The sensitivity was similar to each other if IW was added to LR-5 (72.9% [35/48] for HBA-MRI vs. 70.8% [34/48] for ECA-MRI; p > 0.999).

Conclusion

Extracellular phase washout for HCC diagnosis was comparable between MRIs with both contrast agents, except for tumors < 20 mm. Adding IW could improve the sensitivity for HCC on ECA-MRI in tumors < 20 mm.

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LI-RADS: Past, Present, and Future, From the AJR Special Series on Radiology Reporting and Data Systems. AJR Am J Roentgenol 2021;216:295-304. [DOI: 10.2214/ajr.20.24272] [Citation(s) in RCA: 6] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 02/07/2023]

Min JH, Kang TW, Kim YY, Cha DI, Kim YK, Kim SH, Sinn DH, Ha SY, Kim K. Vanishing washout of hepatocellular carcinoma according to the presence of hepatic steatosis: diagnostic performance of CT and MRI. Eur Radiol 2020;31:3315-3325. [PMID: 33159576 DOI: 10.1007/s00330-020-07438-9] [Citation(s) in RCA: 6] [Impact Index Per Article: 1.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/02/2020] [Revised: 08/14/2020] [Accepted: 10/16/2020] [Indexed: 02/08/2023]

Abstract

OBJECTIVES

To compare the presence of washout and the diagnostic performance of computed tomography (CT) and magnetic resonance imaging (MRI) for hepatocellular carcinoma (HCC) according to the presence of hepatic steatosis.

METHODS

This retrospective study included 566 patients with chronic liver disease who had undergone hepatic resection for hepatic tumors (482 HCCs and 84 non-HCCs) between January 2016 and June 2018 and had available multiphasic CT and MR images. Patients were allocated in the fatty liver (n = 141) or non-fatty liver (n = 425) group according to the presence of hepatic steatosis, defined as lipid droplets in at least 5% of hepatocytes on pathological examination. The presence of HCC washout and the diagnostic performance of CT and MRI for HCC were compared between the groups.

RESULTS

HCC washout was less frequently seen in the fatty liver group than in the non-fatty liver group on CT (61.5% vs. 88.9%, p < 0.001), whereas it was similarly present on MRI in both groups (77.0% vs. 74.4%, p = 0.565). For diagnosis of HCC, the sensitivity (53.3% vs. 80.0%, p < 0.001) and accuracy (53.9% vs. 80.9%, p < 0.001) of CT were lower in the fatty liver group than in the non-fatty liver group. However, for MRI, these values were not significantly different between the groups (p > 0.05).

CONCLUSIONS

Hepatic steatosis significantly decreased the performance of CT for the diagnosis of HCC, whereas it did not significantly alter the performance of MRI.

KEY POINTS

• Unlike MRI, there is vanishing HCC washout on CT caused by the background hepatic steatosis. • The diagnostic performance of CT for the diagnosis of HCC was significantly altered by hepatic steatosis. • The optimal cutoff HU value of the liver parenchyma for the vanishing washout of HCC was < 50 HU on unenhanced CT images.

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Hwang SH, Hong SB, Park S, Han K, Park YN, Kim SY, Park MS. Subcentimeter hepatocellular carcinoma in treatment-naïve patients: noninvasive diagnostic criteria and tumor staging on gadoxetic acid-enhanced MRI. Eur Radiol 2020;31:2321-2331. [PMID: 33044650 DOI: 10.1007/s00330-020-07329-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/29/2020] [Revised: 08/09/2020] [Accepted: 09/18/2020] [Indexed: 10/23/2022]

Abstract

OBJECTIVE

It is controversial to adopt non-invasive diagnostic criteria of hepatocellular carcinoma (HCC) in subcentimeter lesions. This study was aimed to define the optimal noninvasive diagnostic criteria of subcentimeter HCC and to evaluate the effect on tumor staging.

METHODS

We included 110 treatment-naïve patients at risk of HCC and eligible for curative treatment who had subcentimeter lesions (n = 136) on gadoxetic acid-enhanced magnetic resonance imaging (MRI) performed between January 2013 and December 2013. Modified diagnostic criteria for subcentimeter HCC were developed using logistic regression analysis. Accuracies of MR staging with and without using the modified criteria were compared by generalized estimating equation test using pathologic staging as reference standards. Subgroup analysis was performed for patients with co-existing HCC ≥ 1 cm (co-HCC).

RESULTS

The modified criteria (presence of co-HCC, arterial phase hyperenhancement, and hypointensity on transitional phase [TP]) showed 61.5% (95% CI, 41.6-78.2) of sensitivity and 98.2% (95% CI, 93.0-99.5) of specificity. Including subcentimeter HCCs improved the accuracy of MR staging from 84.5 to 94.5% (p = 0.001). Fifty percent of subcentimeter lesions found in patients with co-HCCs were HCC, whereas 5.9% of them without co-HCCs were HCC (p = 0.001). In the subgroup with co-HCCs, the accuracy of MR staging with subcentimeter HCCs was improved from 69.0% to 92.8% (p = 0.001).

CONCLUSIONS

Including subcentimeter HCCs based on the modified diagnostic criteria (co-existing HCC ≥ 1 cm, arterial phase hyperenhancement, and hypointensity on TP) improved MR staging accuracy.

KEY POINTS

• Fifty percent of non-benign appearing subcentimeter lesions found in patients with co-HCCs were HCC, whereas 5.9% of them without co-HCCs were HCC (p = 0.001). • Including subcentimeter HCCs improved the accuracy of MR staging from 84.5 to 94.5% (p = 0.001).

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Piñero F, Tanno M, Aballay Soteras G, Tisi Baña M, Dirchwolf M, Fassio E, Ruf A, Mengarelli S, Borzi S, Fernández N, Ridruejo E, Descalzi V, Anders M, Mazzolini G, Reggiardo V, Marciano S, Perazzo F, Spina JC, McCormack L, Maraschio M, Lagues C, Gadano A, Villamil F, Silva M, Cairo F, Ameigeiras B. Argentinian clinical practice guideline for surveillance, diagnosis, staging and treatment of hepatocellular carcinoma. Ann Hepatol 2020;19:546-569. [PMID: 32593747 DOI: 10.1016/j.aohep.2020.06.003] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.6] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/25/2020] [Revised: 06/05/2020] [Accepted: 06/10/2020] [Indexed: 02/08/2023]

Affiliation(s)

Federico Piñero Hepatology and Liver Unit, Hospital Universitario Austral, School of Medicine, Austral University, B1629HJ Buenos Aires, Argentina.
Mario Tanno Hospital Centenario de Rosario, Santa Fe, Argentina
Gabriel Aballay Soteras Hospital Argerich, Ciudad de Buenos Aires, Argentina
Matías Tisi Baña Internal Medicine and Epidemiology Department, Hospital Universitario Austral, School of Medicine, Austral University, B1629HJ Buenos Aires, Argentina
Melisa Dirchwolf Hospital Privado de Rosario, Santa Fe, Argentina
Eduardo Fassio Hospital Alejandro Posadas, Buenos Aires, Argentina
Andrés Ruf Hospital Privado de Rosario, Santa Fe, Argentina
Silvia Mengarelli Hospital San Roque, Córdoba, Argentina
Silvia Borzi Instituto Rossi, La Plata, Buenos Aires, Argentina
Nora Fernández Hospital Británico, Ciudad de Buenos Aires, Argentina
Ezequiel Ridruejo Hepatology and Liver Unit, Hospital Universitario Austral, School of Medicine, Austral University, B1629HJ Buenos Aires, Argentina; Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Ciudad de Buenos Aires, Argentina
Valeria Descalzi Fundación Favaloro, Ciudad de Buenos Aires, Argentina
Margarita Anders Hospital Alemán, Ciudad de Buenos Aires, Argentina
Guillermo Mazzolini Hepatology and Liver Unit, Hospital Universitario Austral, School of Medicine, Austral University, B1629HJ Buenos Aires, Argentina
Virginia Reggiardo Hospital Argerich, Ciudad de Buenos Aires, Argentina
Sebastián Marciano Hospital Italiano de Buenos Aires, Argentina
Florencia Perazzo Hospital Británico, Ciudad de Buenos Aires, Argentina
Juan Carlos Spina Hospital Italiano de Buenos Aires, Argentina
Lucas McCormack Hospital Alemán, Ciudad de Buenos Aires, Argentina
Martín Maraschio Hospital Privado de Córdoba, Argentina
Cecilia Lagues Hepatology and Liver Unit, Hospital Universitario Austral, School of Medicine, Austral University, B1629HJ Buenos Aires, Argentina
Adrián Gadano Hospital Italiano de Buenos Aires, Argentina
Federico Villamil Hospital Británico, Ciudad de Buenos Aires, Argentina
Marcelo Silva Hepatology and Liver Unit, Hospital Universitario Austral, School of Medicine, Austral University, B1629HJ Buenos Aires, Argentina
Fernando Cairo Hospital Británico, Ciudad de Buenos Aires, Argentina
Beatriz Ameigeiras Hospital Ramos Mejía, Ciudad de Buenos Aires, Argentina

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Lee S, Kim SS, Bae H, Shin J, Yoon JK, Kim MJ. Application of Liver Imaging Reporting and Data System version 2018 ancillary features to upgrade from LR-4 to LR-5 on gadoxetic acid-enhanced MRI. Eur Radiol 2020;31:855-863. [PMID: 32809162 DOI: 10.1007/s00330-020-07146-4] [Citation(s) in RCA: 15] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/23/2020] [Revised: 05/29/2020] [Accepted: 08/04/2020] [Indexed: 02/07/2023]

Abstract

OBJECTIVES

The current LR-5 criteria of Liver Imaging Reporting and Data System (LI-RADS) determined by only major features provide high specificity, but unsatisfactorily low sensitivity for the noninvasive diagnosis of hepatocellular carcinoma (HCC). This study aimed to identify significant ancillary features (AFs) in LI-RADS version 2018 and develop the upgraded LR-5 criteria to improve diagnostic performance on gadoxetic acid-enhanced magnetic resonance imaging (MRI).

METHODS

This retrospective study included 280 patients (366 observations including 281 HCCs) at high-risk for HCC who underwent gadoxetic acid-enhanced MRI between 2015 and 2017. Two readers evaluated major features and AFs for each observation and assigned a LI-RADS category. Independently significant AFs were identified through logistic regression analysis. Upgraded LR-5 criteria were developed by combining independently significant AFs with LR-4 assigned by major features alone. Sensitivities and specificities of the diagnostic criteria were compared using McNemar's test.

RESULTS

Two of the AFs favoring malignancy in general (mild-moderate T2 hyperintensity and hepatobiliary phase hypointensity) and two of the AFs favoring HCC in particular (nonenhancing "capsule" and mosaic architecture) were independently significant features for diagnosing HCC. By using the upgraded LR-5 criteria (LR-4 by major features alone + each aforementioned AF), sensitivities were significantly increased (69.4-76.9%) compared with the standard LR-5 (66.2%; all, p ≤ 0.004), whereas specificities (95.3-96.5%) were not significantly different (96.5%; all, p > 0.999).

CONCLUSIONS

Independently significant AFs may be used to upgrade from LR-4 to LR-5 to improve sensitivity without impairing specificity on gadoxetic acid-enhanced MRI.

KEY POINTS

• Independently significant AFs for HCC on gadoxetic acid-enhanced MRI were mild-moderate T2 hyperintensity, hepatobiliary phase hypointensity, nonenhancing "capsule," and mosaic architecture. • When LR-4 criteria by major features alone in combination with significant AFs were upgraded to LR-5, sensitivities were higher than the standard LR-5, without impairing specificity. • Independently significant ancillary features in Liver Imaging Reporting and Data System version 2018 may be used to upgrade from LR-4 to LR-5 to improve sensitivity without impairing specificity on gadoxetic acid-enhanced MRI.

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Kim JH, Joo I, Lee JM. Atypical Appearance of Hepatocellular Carcinoma and Its Mimickers: How to Solve Challenging Cases Using Gadoxetic Acid-Enhanced Liver Magnetic Resonance Imaging. Korean J Radiol 2020;20:1019-1041. [PMID: 31270973 PMCID: PMC6609440 DOI: 10.3348/kjr.2018.0636] [Citation(s) in RCA: 37] [Impact Index Per Article: 7.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/11/2018] [Accepted: 03/17/2019] [Indexed: 02/06/2023] Open

A proposal for a useful algorithm to diagnose small hepatocellular carcinoma on MRI. Eur J Gastroenterol Hepatol 2020;32:74-79. [PMID: 31211723 DOI: 10.1097/meg.0000000000001476] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/10/2022]

Erkan B, Meier J, Clark TJ, Kaplan J, Lambert JR, Chang S. Non-invasive diagnostic criteria of hepatocellular carcinoma: Comparison of diagnostic accuracy of updated LI-RADS with clinical practice guidelines of OPTN-UNOS, AASLD, NCCN, EASL-EORTC, and KLSCG-NCC. PLoS One 2019;14:e0226291. [PMID: 31821360 PMCID: PMC6903758 DOI: 10.1371/journal.pone.0226291] [Citation(s) in RCA: 14] [Impact Index Per Article: 2.3] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/12/2019] [Accepted: 11/22/2019] [Indexed: 12/15/2022] Open

Abstract

Purpose

To retrospectively compare the diagnostic performance of different noninvasive diagnostic criteria of HCC including LI-RADS, OPTN-UNOS, AASLD, NCCN, EASL-EORTC, KLCSG-NCC.

Materials and methods

We reviewed the medical records of 3,491 pathologically examined liver lesions from January-2011 to January-2015 in our institution. 195 lesions in 133 patients (M:F = 100:33) with chronic hepatitis B/C and/or cirrhosis for any etiology were finally included in our study, with 98 lesions ≥ 2 cm, 72 lesions between 1–2 cm, and 25 lesions < 1 cm. The main comparison was made with the largest nodules of each patient (n = 133). The lesions were retrospectively evaluated for the diagnosis of HCC on DCE-CT or MR using different noninvasive diagnostic criteria including LI-RADS, OPTN-UNOS, AASLD, NCCN, EASL-EORTC, and KLCSG-NCC. With pathological evaluation serving as a gold-standard, sensitivity, specificity, PPV and NPV as well as accuracy of the diagnostic criteria were calculated.

Results

There was no statistically significant differences in diagnostic accuracy among noninvasive diagnostic criteria. For 133 lesions of the largest lesion per patient, the overall accuracy was highest with LI-RADS criteria (89.3%) and the overall sensitivity was highest with LI-RADS, AASLD, NCCN criteria (all 89.5%). For 1–2 cm lesions, sensitivity decreased for all criteria in the following order: EASL-EORTC (59.1%), KLCSG-NCC (58.3%), LI-RADS, AASLD, NCCN (all 56.5%), and OPTN-UNOS (22.7%) criteria. OPTN-UNOS had the highest specificity in cirrhotic livers, 91.7%.

Conclusions

The current noninvasive diagnostic criteria of HCC have no statistically significant difference in diagnostic accuracy. Overall, LI-RADS had the highest sensitivity and accuracy among the guidelines. OPTN had the highest specificity for cirrhotic livers.

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Yao B, Li Y, Wang L, Chen T, Niu Y, Liu Q, Liu Z. MicroRNA-3194-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by decreasing Wnt/β-catenin signaling through targeting BCL9. ARTIFICIAL CELLS, NANOMEDICINE, AND BIOTECHNOLOGY 2019;47:3885-3895. [PMID: 31561723 DOI: 10.1080/21691401.2019.1670190] [Citation(s) in RCA: 24] [Impact Index Per Article: 4.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 07/16/2019] [Accepted: 09/04/2019] [Indexed: 02/08/2023]

Di Tommaso L, Spadaccini M, Donadon M, Personeni N, Elamin A, Aghemo A, Lleo A. Role of liver biopsy in hepatocellular carcinoma. World J Gastroenterol 2019;25:6041-6052. [PMID: 31686761 PMCID: PMC6824282 DOI: 10.3748/wjg.v25.i40.6041] [Citation(s) in RCA: 98] [Impact Index Per Article: 16.3] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/29/2019] [Revised: 10/04/2019] [Accepted: 10/17/2019] [Indexed: 02/06/2023] Open

Al-Sharhan F, Dohan A, Barat M, Feddal A, Terris B, Pol S, Mallet V, Soyer P. MRI presentation of hepatocellular carcinoma in non-alcoholic steatohepatitis (NASH). Eur J Radiol 2019;119:108648. [DOI: 10.1016/j.ejrad.2019.108648] [Citation(s) in RCA: 7] [Impact Index Per Article: 1.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/01/2019] [Revised: 08/11/2019] [Accepted: 08/27/2019] [Indexed: 12/12/2022]

Performance of gadoxetic acid MRI and diffusion-weighted imaging for the diagnosis of early recurrence of hepatocellular carcinoma. Eur Radiol 2019;30:186-194. [DOI: 10.1007/s00330-019-06351-0] [Citation(s) in RCA: 13] [Impact Index Per Article: 2.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/22/2019] [Revised: 06/17/2019] [Accepted: 07/01/2019] [Indexed: 02/07/2023]

Vernuccio F, Cannella R, Meyer M, Choudhoury KR, Gonzáles F, Schwartz FR, Gupta RT, Bashir MR, Furlan A, Marin D. LI-RADS: Diagnostic Performance of Hepatobiliary Phase Hypointensity and Major Imaging Features of LR-3 and LR-4 Lesions Measuring 10-19 mm With Arterial Phase Hyperenhancement. AJR Am J Roentgenol 2019;213:W57-W65. [PMID: 31039012 DOI: 10.2214/ajr.18.20979] [Citation(s) in RCA: 28] [Impact Index Per Article: 4.7] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 02/08/2023]