Minireview of relationship between perfluoroalkyl and polyfluoroalkyl substances and hypertension

doi:10.4330/wjc.125866

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Cardiol. Oct 26, 2026; 18(10): 125866
Published online Oct 26, 2026. doi: 10.4330/wjc.125866

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Figure 1 Chemical structural formula of polyfluoroalkyl substances. PFOA: Perfluorooctanoic acid; PFOS: Perfluorooctane sulfonate.

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Figure 2 Potential mechanisms through which polyfluoroalkyl substances affect blood pressure. Doubao AI was used solely for the generation of the mechanistic figure included in the manuscript. PFAS: Perfluoroalkyl and polyfluoroalkyl substances; PPAR: Peroxisome proliferator-activated receptors; ROS: Reactive oxygen species; NO: Nitric oxide.

Citation: Li J, Chen L. Minireview of relationship between perfluoroalkyl and polyfluoroalkyl substances and hypertension. World J Cardiol 2026; 18(10): 125866
URL: https://www.wjgnet.com/1949-8462/full/v18/i10/125866.htm
DOI: https://dx.doi.org/10.4330/wjc.125866

Li J, Chen L. Minireview of relationship between perfluoroalkyl and polyfluoroalkyl substances and hypertension. World J Cardiol 2026; 18(10): 125866 [DOI: 10.4330/wjc.125866]

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