Published online May 26, 2017. doi: 10.4330/wjc.v9.i5.407
Peer-review started: November 3, 2016
First decision: January 14, 2017
Revised: January 20, 2017
Accepted: March 12, 2017
Article in press: March 13, 2017
Published online: May 26, 2017
Core tip: Heart failure (HF) is a major cause of late morbidity and mortality after myocardial infarction. Several approaches exist for early identification of patients at risk of HF, including clinical and angiographic scoring, cardiac imaging, and invasive coronary physiology, but these are currently poorly integrated. Here we provide an overview of the incidence, mechanisms, and outcomes of HF following myocardial infarction in the era of primary percutaneous coronary intervention, and discuss HF risk-stratification for the individual patient. Looking ahead, accurate and early prediction of HF will allow targeting of novel therapeutic agents to high-risk patients before ventricular remodelling and clinical HF have become established.