Published online Feb 26, 2015. doi: 10.4330/wjc.v7.i2.52
Peer-review started: May 29, 2014
First decision: July 18, 2014
Revised: December 31, 2014
Accepted: January 15, 2015
Article in press: January 19, 2015
Published online: February 26, 2015
Core tip: After myocardial infarction, the heart undergoes extensive myocardial remodeling through the accumulation of fibrous tissue in both the infarcted and noninfarcted myocardium, which distorts tissue structure, increases tissue stiffness, and accounts for ventricular dysfunction. There is growing clinical consensus that exercise training may beneficially alter the course of post-myocardial infarction (MI) myocardial remodeling and improve cardiac function. This review summarizes the present state of knowledge regarding the effect of post-MI exercise training on infarcted hearts.