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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Sep 26, 2014; 6(9): 1006-1021
Published online Sep 26, 2014. doi: 10.4330/wjc.v6.i9.1006
Published online Sep 26, 2014. doi: 10.4330/wjc.v6.i9.1006
Serum creatinine role in predicting outcome after cardiac surgery beyond acute kidney injury
Mahdi Najafi, Tehran Heart Center, Tehran University of Medical Sciences, Tehran 1411713138, Iran
Author contributions: Najafi M solely contributed to this paper.
Correspondence to: Mahdi Najafi, MD, Tehran Heart Center, Tehran University of Medical Sciences, North Karegar Ave, Tehran 1411713138, Iran. najafik@sina.tums.ac.ir
Telephone: +98-21-88029674 Fax: +98-21-88029724
Received: January 11, 2014
Revised: April 7, 2014
Accepted: July 12, 2014
Published online: September 26, 2014
Revised: April 7, 2014
Accepted: July 12, 2014
Published online: September 26, 2014
Core Tip
Core tip: This manuscript aims to review the latest achievements in the diagnosis and treatment of acute kidney injury (AKI). Despite much progress in recent years, especially in the development of novel biomarkers, serum creatinine still plays the major role. Creatinine is not only the mainstay of definition, diagnosis and prediction of AKI, but also the most important predictor of outcome after cardiac surgery, including mortality and morbidity as well as hospital length of stay.