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World J Cardiol. Oct 26, 2021; 13(10): 526-532
Published online Oct 26, 2021. doi: 10.4330/wjc.v13.i10.526
Lipid lowering in patients 75 years and older
Umidakhon Makhmudova, P Christian Schulze, Harry R Davis, Oliver Weingärtner
Umidakhon Makhmudova, P Christian Schulze, Oliver Weingärtner, Klinik für Innere Medizin I, Universitätsklinikum Jena, Jena 07747, Germany
Harry R Davis, Synergy Partners RD Solutions, Synergy Partners RD Solutions, Gaithersburg, MD 20850, United States
Author contributions: Makhmudova U, Schulze PC, Davis HR and Weingärtner O wrote the manuscript and designed figures; All authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Oliver Weingärtner, MD, PhD, Adjunct Professor, Klinik für Innere Medizin I, Universitätsklinikum Jena, Jena 07747, Germany. oliver.weingaertner@med.uni-jena.de
Received: April 1, 2021
Peer-review started: April 1, 2021
First decision: July 6, 2021
Revised: July 12, 2021
Accepted: September 8, 2021
Article in press: September 8, 2021
Published online: October 26, 2021
Core Tip

Core Tip: The review summarizes the evidence of lipid-lowering therapies in patients 75 years and older, and discusses the possible underlying pathophysiological mechanisms and calls for a change in future dyslipidemia guidelines.