Henning RJ. Diagnosis and treatment of heart failure with preserved left ventricular ejection fraction. World J Cardiol 2020; 12(1): 7-25 [PMID: 31984124 DOI: 10.4330/wjc.v12.i1.7]
Corresponding Author of This Article
Robert J Henning, MD, Doctor, Emeritus Professor, College of Public Health, University of South Florida, 13201 Bruce B Downs Blvd, Tampa, FL 33612, United States. roberthenningmd@gmail.com
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Jan 26, 2020; 12(1): 7-25 Published online Jan 26, 2020. doi: 10.4330/wjc.v12.i1.7
Diagnosis and treatment of heart failure with preserved left ventricular ejection fraction
Robert J Henning
Robert J Henning, College of Public Health, University of South Florida, Tampa, FL33612, United States
Author contributions: The author finished manuscript alone.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Robert J Henning, MD, Doctor, Emeritus Professor, College of Public Health, University of South Florida, 13201 Bruce B Downs Blvd, Tampa, FL 33612, United States. roberthenningmd@gmail.com
Received: July 12, 2019 Peer-review started: July 17, 2019 First decision: August 2, 2019 Revised: October 17, 2015 Accepted: November 26, 2019 Article in press: November 26, 2019 Published online: January 26, 2020
Core Tip
Core tip: Three million people in United States have heart failure with normal left ventricular systolic function but abnormal diastolic function due to increased myocardial stiffness. These patients are often elderly women with hypertension, ischemic heart disease, atrial fibrillation, obesity, diabetes mellitus, renal disease, or obstructive lung disease. The annual mortality rate of these patients is 8%-12% per year. The diagnosis is based on history, physical examination, laboratory data, echocardiography, and, when necessary, by cardiac catheterization. These patients often require weight reduction, an exercise program, aggressive control of blood pressure and heart rate, and diuretics. If significant coronary heart disease is present, coronary revascularization should be considered.
