Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Jan 26, 2020; 12(1): 35-43
Published online Jan 26, 2020. doi: 10.4330/wjc.v12.i1.35
Published online Jan 26, 2020. doi: 10.4330/wjc.v12.i1.35
Impact of training specificity on exercise-induced cardiac troponin elevation in professional athletes: A pilot study
Johan O Wedin, Department of Clinical Physiology, Sundsvall County Hospital, Sundsvall 851 86, Sweden
Johan O Wedin, Nicolena S Nyberg, Anders E Henriksson, Department of Clinical Chemistry, Sundsvall County Hospital, Sundsvall 851 86, Sweden
Anders E Henriksson, Department of Natural Sciences, Mid Sweden University, Sundsvall 851 70, Sweden
Author contributions: Wedin JO and Henriksson AE were equally involved in designing the study, collecting and analyzing the data, and preparing the manuscript; Wedin JO, Nyberg NS, and Henriksson AE reviewed and revised the final version of the manuscript.
Institutional review board statement: Please see the uploaded files where you can find the approved Institutional Review Board Statement.
Informed consent statement: Please see the uploaded files where we attached the informed consent forms for all participants.
Conflict-of-interest statement: The authors report no relevant conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Anders E Henriksson, MD, PhD, Professor, Department of Clinical Chemistry, Sundsvall County Hospital, Sundsvall 851 86, Sweden. anders.henriksson@rvn.se
Received: May 31, 2019
Peer-review started: June 4, 2019
First decision: August 2, 2019
Revised: September 20, 2019
Accepted: October 14, 2019
Article in press: October 15, 2019
Published online: January 26, 2020
Peer-review started: June 4, 2019
First decision: August 2, 2019
Revised: September 20, 2019
Accepted: October 14, 2019
Article in press: October 15, 2019
Published online: January 26, 2020
Core Tip
Core tip: Exercise-induced cardiac troponin elevation is common after continuous exercise, but the response to intermittent exercise is less investigated. Nine professional athletes adapted to intermittent exercise underwent serial assessment of high-sensitivity cardiac troponin T (hs-cTnT) after continuous exercise and intermittent exercise tests. The intermittent exercise test induced higher levels of hs-cTnT compared to the continuous exercise test. The peak hs-cTnT concentration was observed 6 h after the exercise tests. The principle of specificity training and timing of blood sampling should be considered when designing future studies to avoid misinterpretation of hs-cTnT elevation.