Díez-delhoyo F, Gutiérrez-Ibañes E, Loughlin G, Sanz-Ruiz R, Vázquez-Álvarez ME, Sarnago-Cebada F, Angulo-Llanos R, Casado-Plasencia A, Elízaga J, Diáz FFA. Coronary physiology assessment in the catheterization laboratory. World J Cardiol 2015; 7(9): 525-538 [PMID: 26413229 DOI: 10.4330/wjc.v7.i9.525]
Corresponding Author of This Article
Enrique Gutiérrez-Ibañes, MD, Instituto de Investigación Sanitaria Gregorio Marañón, Servicio de Cardiología, Departamento de Medicina, Universidad Complutense de Madrid, Calle Dr Esquerdo 46, 28007 Madrid, Spain. e-guti@hotmail.es
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Sep 26, 2015; 7(9): 525-538 Published online Sep 26, 2015. doi: 10.4330/wjc.v7.i9.525
Coronary physiology assessment in the catheterization laboratory
Felipe Díez-delhoyo, Enrique Gutiérrez-Ibañes, Gerard Loughlin, Ricardo Sanz-Ruiz, María Eugenia Vázquez-Álvarez, Fernando Sarnago-Cebada, Rocío Angulo-Llanos, Ana Casado-Plasencia, Jaime Elízaga, Francisco Fernández Avilés Diáz
Felipe Díez-delhoyo, Enrique Gutiérrez-Ibañes, Gerard Loughlin, Ricardo Sanz-Ruiz, María Eugenia Vázquez-Álvarez, Fernando Sarnago-Cebada, Rocío Angulo-Llanos, Ana Casado-Plasencia, Francisco Fernández Avilés Diáz, Jaime Elízaga-Corrales, Instituto de Investigación Sanitaria Gregorio Marañón, Servicio de Cardiología, Departamento de Medicina, Universidad Complutense de Madrid, 28007 Madrid, Spain
Author contributions: All authors helped with the writing of the article.
Conflict-of-interest statement: None declared.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Enrique Gutiérrez-Ibañes, MD, Instituto de Investigación Sanitaria Gregorio Marañón, Servicio de Cardiología, Departamento de Medicina, Universidad Complutense de Madrid, Calle Dr Esquerdo 46, 28007 Madrid, Spain. e-guti@hotmail.es
Telephone: +34-65-3992157
Received: May 23, 2015 Peer-review started: May 26, 2015 First decision: June 24, 2015 Revised: July 10, 2015 Accepted: July 24, 2015 Article in press: July 27, 2015 Published online: September 26, 2015
Abstract
Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of coronary vascular physiology and of the methods currently available for its characterization can improve the diagnostic and prognostic accuracy of invasive assessment of the coronary circulation, and help improve clinical decision-making. In this article we summarize the current methods available for a thorough assessment of coronary physiology.
Core tip: Assessment of the coronary circulation in the cathlab cannot be limited to angiography nowadays. The interventional cardiologist needs to be aware of current knowledge on coronary physiology and of the methods and measurements available for its characterization in clinical practice and research. In this article we review the main methods to assess the functional severity of coronary stenosis, myocardial blood flow, microvascular circulation, and endothelial function.
