Case Report
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Cardiol. Apr 26, 2012; 4(4): 128-129
Published online Apr 26, 2012. doi: 10.4330/wjc.v4.i4.128
Eosinophilia: Rare cause of arterial thrombosis and cardioembolic stroke in childhood
Sanjeev Kumar Sharma, Suman Kumar, Tulika Seth, Pravas Mishra, Manoranjan Mahapatra
Sanjeev Kumar Sharma, Suman Kumar, Tulika Seth, Pravas Mishra, Manoranjan Mahapatra, Department of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India
Author contributions: Sharma SK and Kumar S collected the clinical data; Seth T and Mishra P analysed the manuscript and did the critical review; Mahapatra M gave the final approval for the manuscript.
Correspondence to: Dr. Tulika Seth, Department of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India. tuliseth@yahoo.com
Telephone: +91-98-68397236 Fax: +91-11-26593363
Received: December 19, 2011
Revised: February 22, 2012
Accepted: February 29, 2012
Published online: April 26, 2012
Abstract

Eosinophilia has been reported as a very rare cause of stroke in children. The thrombotic event may be either due to cardiac damage induced by eosinophils and their granular protein, that is, the major basic protein, or the systemic hypercoagulable state induced by eosinophilia. We report here a case of eosinophilia whose initial presentation was recurrent strokes and cardiac and arterial thrombosis.

Keywords: Eosinophilia, Cardioembolic stroke, Thrombosis, Low molecular weight heparin, Warfarin