Truyen TTTT. Same day percutaneous coronary intervention discharge: From exception to expectation. World J Cardiol 2026; 18(9): 120352 [DOI: 10.4330/wjc.120352]
Corresponding Author of This Article
Thien Tan Tri Tai Truyen, MD, Researcher, School of Medicine, Nam Can Tho University, 168 Nguyen Van Cu Street, Ninh Kieu District, Can Tho 94159, Viet Nam. taitruyenmd@gmail.com
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Cardiac & Cardiovascular Systems
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editorial
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Truyen TTTT. Same day percutaneous coronary intervention discharge: From exception to expectation. World J Cardiol 2026; 18(9): 120352 [DOI: 10.4330/wjc.120352]
World J Cardiol. Sep 26, 2026; 18(9): 120352 Published online Sep 26, 2026. doi: 10.4330/wjc.120352
Same day percutaneous coronary intervention discharge: From exception to expectation
Thien Tan Tri Tai Truyen
Thien Tan Tri Tai Truyen, School of Medicine, Nam Can Tho University, Can Tho 94159, Viet Nam
Author contributions: Truyen TTTT contributed to conceptualization, writing - original draft, and writing - review and editing.
AI contribution statement: Portions of this manuscript were edited using AI tools (Anthropic Claude AI) solely for language refinement. The authors carefully reviewed and verified all AI-assisted outputs and take full responsibility for the scientific content of the manuscript.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Corresponding author: Thien Tan Tri Tai Truyen, MD, Researcher, School of Medicine, Nam Can Tho University, 168 Nguyen Van Cu Street, Ninh Kieu District, Can Tho 94159, Viet Nam. taitruyenmd@gmail.com
Received: February 24, 2026 Revised: July 24, 2026 Accepted: August 5, 2026 Published online: September 26, 2026 Processing time: 206 Days and 23.8 Hours
Abstract
Same day discharge after elective percutaneous coronary intervention (PCI) is increasingly adopted, particularly with transradial access, however longterm safety evidence has been limited. Klocek et al recently published a study in the World Journal of Cardiology provide timely real-world data from a single ambulatory surgical center: 787 consecutive PCIs (2018-2023) with a median discharge time of 150 minutes. Early outcomes were reassuring: Within 24 hours there were no deaths, strokes, emergent coronary artery bypass grafting, transfers for overnight care, or hospitalizations; by 30 days, unplanned cardiovascular hospitalizations occurred in 0.7% and there were no deaths or strokes. Two-year events remained low: Death 1.93%, myocardial infarction 0.85%, target vessel revascularization 7.62%, and stroke 0.17%. Subgroup outcomes in higher-risk anatomy - 25 left main and 332 left anterior descending (115 proximal) procedures - were reassuring but based on small numbers and remain hypothesis-generating rather than confirmatory, particularly for left main disease. Femoral cases showed higher two-year target vessel revascularization (21.84% vs 5.85%; P < 0.001) without differences in death or myocardial infarction, reflecting greater baseline comorbidity rather than access site alone. Interpreted alongside the randomized and consensus evidence that preceded it, including the 2018 Society for Cardiovascular Angiography and Interventions shift from anatomy-based exclusions to milestone-based discharge readiness, this hypothesis-generating study supports the feasibility of very early discharge after PCI in experienced centers with structured follow-up and standardized protocols. Nevertheless, its retrospective, single-center design, absence of an inpatient comparator, and capture of unplanned hospitalizations only to 30 days temper conclusions. Future multicenter randomized trials and standardized post-discharge pathways are warranted.
Core Tip: Same-day discharge after elective percutaneous coronary intervention appears safe and efficient in experienced centers using predominantly radial access and structured follow-up. Early outcomes were excellent and two-year event rates remained low; findings in left main and proximal left anterior descending disease were reassuring but, given small numbers, are hypothesis-generating. Early discharge should pair with careful selection, robust secondary prevention, and rapid re-entry pathways; multicenter randomized trials are warranted.
