Nguyen Nguyen N, Assad JG, Femia G, Schuster A, Otton J, Nguyen TL. Role of cardiac magnetic resonance imaging in troponinemia syndromes. World J Cardiol 2022; 14(4): 190-205 [PMID: 35582465 DOI: 10.4330/wjc.v14.i4.190]
Corresponding Author of This Article
Tuan Le Nguyen, FRACP, MBBS, PhD, Staff Physician, Department of Cardiology, Liverpool Hospital, Locked Bag 7103, Liverpool 2170, NSW, Australia. nguyenletuan@hotmail.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Apr 26, 2022; 14(4): 190-205 Published online Apr 26, 2022. doi: 10.4330/wjc.v14.i4.190
Role of cardiac magnetic resonance imaging in troponinemia syndromes
Nhung Nguyen Nguyen, Joseph George Assad, Giuseppe Femia, Andreas Schuster, James Otton, Tuan Le Nguyen
Nhung Nguyen Nguyen, Joseph George Assad, James Otton, Tuan Le Nguyen, Department of Cardiology, Liverpool Hospital, Liverpool 2170, NSW, Australia
Giuseppe Femia, Department of Cardiology, Campbelltown Hospital, Campbelltown 2560, NSW, Australia
Andreas Schuster, Department of Cardiology and Pneumology, University Medical Center, Göttingen 37075, Germany
Author contributions: Nguyen Nguyen N was responsible for concept and design of manuscript, and wrote the first original draft (except section on Takotsubo cardiomyopathy); Assad JG provided the first original draft for the Takotsubo cardiomyopathy section and Table 1; Assad JG, Femia G, Otton J and Schuster A collected or provided the cardiac magnetic resonance images; Nguyen Nguyen N, Femia G, Schuster A, Otton J and Nguyen TL were the main contributors towards critical revisions related to important intellectual content of the manuscript; and all authors provided the approval of the final version of the article to be published.
Conflict-of-interest statement: All authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tuan Le Nguyen, FRACP, MBBS, PhD, Staff Physician, Department of Cardiology, Liverpool Hospital, Locked Bag 7103, Liverpool 2170, NSW, Australia. nguyenletuan@hotmail.com
Received: March 18, 2021 Peer-review started: March 18, 2021 First decision: September 29, 2021 Revised: November 13, 2022 Accepted: April 3, 2022 Article in press: April 3, 2022 Published online: April 26, 2022
Abstract
Cardiac magnetic resonance imaging (MRI) is an evolving technology, proving to be a highly accurate tool for quantitative assessment. Most recently, it has been increasingly used in the diagnostic and prognostic evaluation of conditions involving an elevation in troponin or troponinemia. Although an elevation in troponin is a nonspecific marker of myocardial tissue damage, it is a frequently ordered investigation leaving many patients without a specific diagnosis. Fortunately, the advent of newer cardiac MRI protocols can provide additional information. In this review, we discuss several conditions associated with an elevation in troponin such as myocardial infarction, myocarditis, Takotsubo cardiomyopathy, coronavirus disease 2019 related cardiac dysfunction and athlete’s heart syndrome.
Core tip: Cardiac magnetic resonance has excellent spatial resolution to assess ventricular volumes and function. It is also continuing to evolve to provide key diagnostic and prognostic information particularly through the use of gadolinium contrast agent for the conditions presented in this review.
