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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Biol Chem. Feb 26, 2016; 7(1): 78-87
Published online Feb 26, 2016. doi: 10.4331/wjbc.v7.i1.78
Published online Feb 26, 2016. doi: 10.4331/wjbc.v7.i1.78
RNA-binding proteins related to stress response and differentiation in protozoa
Lysangela Ronalte Alves, Samuel Goldenberg, Inst. Carlos Chagas, Fiocruz - PR, Curitiba, Parana 81350-010, Brazil
Author contributions: Alves LR and Goldenberg S wrote the paper.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Samuel Goldenberg, Professor, Inst. Carlos Chagas, Fiocruz - PR, Algacyr Munhoz Madder 3775, Curitiba, Parana 81350-010, Brazil. sgoldenb@fiocruz.br
Telephone: +55-41-33163230
Received: May 29, 2015
Peer-review started: May 29, 2015
First decision: August 19, 2015
Revised: October 25, 2015
Accepted: November 16, 2015
Article in press: November 17, 2015
Published online: February 26, 2016
Peer-review started: May 29, 2015
First decision: August 19, 2015
Revised: October 25, 2015
Accepted: November 16, 2015
Article in press: November 17, 2015
Published online: February 26, 2016
Core Tip
Core tip: RNA-binding proteins (RBPs) are numerous and widely distributed in nature. In addition to having different domains, these proteins are key modulators of gene expression and are involved in the cellular response to environmental changes, cell differentiation and cell death. In protozoa RBPs are crucial for the rapid gene expression remodeling that occurs in the course of cell differentiation or the stress response.