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World J Biol Chem. May 27, 2022; 13(3): 66-71
Published online May 27, 2022. doi: 10.4331/wjbc.v13.i3.66
Progesterone in gender-affirming therapy of trans women
Charalampos Milionis, Ioannis Ilias, Eftychia Koukkou
Charalampos Milionis, Ioannis Ilias, Eftychia Koukkou, Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou Hospital, Athens GR-11521, Greece
Author contributions: Milionis C and Ilias I performed the majority of the writing and prepared the table; Ilias I and Koukkou E provided input in writing the paper; Koukkou E coordinated the writing of the paper.
Conflict-of-interest statement: The authors state that they have no conflict of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ioannis Ilias, MD, PhD, Consultant Physician-Scientist, Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou Hospital, 2, Elena Venizelou Square, Athens GR-11521, Greece. iiliasmd@yahoo.com
Received: December 20, 2021
Peer-review started: December 20, 2021
First decision: February 21, 2022
Revised: February 28, 2022
Accepted: April 22, 2022
Article in press: April 22, 2022
Published online: May 27, 2022
Core Tip

Core Tip: The addition of bioidentical progesterone to the gender-affirming treatment of trans women may be beneficial in many ways. However, since relevant studies are lacking, further research is needed.