Copyright ©The Author(s) 2015.
World J Gastrointest Surg. Nov 27, 2015; 7(11): 313-318
Published online Nov 27, 2015. doi: 10.4240/wjgs.v7.i11.313
Table 1 Studies evaluating the natural history of acute diverticulitis
Ref.No. of patientsType of studyFURecurrence rateComments
Lahat et al[38], 2013261Prospective88 mo21.5%21% operated, 46.6% asymptomatic
Buchs et al[17], 2013280Prospective24 mo16.4%RF: CRP > 240
Humes and West[35], 20122950Population-based cohort study7.99 yr-Risk of fistula correlates to the number of prior episodes of diverticulitis
Binda et al[36], 2012743Multicenter, retro-prospective10.7 yr17.2%1RF: < 40 yr, 3 episodes
Hall et al[16], 2011672Retrospective42.8 mo36%RF: Family history, length of involved colon > 5 cm, retroperitoneal abscess
Mäkelä et al[20], 2010555Retrospective-42%38% of recurrence diagnosed on clinical findings
Eglinton et al[26], 2010320Retrospective101 mo18.8%4.7% more than one recurrent episode
Pittet et al[19], 2009271Retrospective-25%Similar severity
Mueller et al[48], 2005252Retrospective89 mo47% (with 10% readmitted)Based on symptoms
Anaya and Flum[27], 200525058Cohort study, retrospective-19%RF: < 50 yr, number of recurrent episodes
Broderick-Villa et al[28], 20053165 (2366 managed conservatively)Cohort study, retrospective8.9 yr13.3%RF: < 50 yr, charlson comorbidity index ≥ 1
Biondo et al[40], 2002327Retrospective24-90 mo15.9%Age not a RF
Chautems et al[15], 2002118Prospective9.5 yr31%Considering only patients undergoing an operation
Somasekar et al[34], 2002108Two-center, retrospective-2.7%1Only patients with complicated disease
Mäkelä et al[43], 1998366Retrospective-22%RF: < 50 yr, male
Ambrosetti et al[44], 1997300Prospective46 mo2%RF: Radiological signs of complicated first episode
Parks[14], 1969317Retrospective-24.6%Only readmitted patients