Reinforced tissue matrix to strengthen the abdominal wall following reversal of temporary ostomies or to treat incisional hernias

Table 1 Preoperative data: Patient demographics and hernia type, n (%)

Number of patients	n = 28
Sex
Male	16 (57.1)
Female	12 (42.9)
Age, yr	58.5 ± 16.3
BMI, kg/m2	26.2 ± 4.1
Patient type
Stoma-site reinforcement	21 (75.0)
Incisional	4 (14.3)
Stoma-site/incisional	3 (10.7)
CDC wound class
Class I: Clean	3 (10.7)
Class II: Clean/contaminated	2 (7.1)
Class III: Contaminated	23 (82.1)
Recurrent	5 (17.9)
Prior hernia repairs	5 (17.9)
Prior wound infection	6 (21.4)
Transplant patient	0 (0)
Stoma present	22 (78.6)
Cancer	17 (60.7)
Immunosuppression/steroid use	19 (67.9)
Hypoalbuminemia (albumin < 3.7 g/dL)	12 (42.9)
Diabetes	10 (35.7)
COPD/chronic cough	8 (28.6)
Smoking	8 (28.6)
MRSA	0 (0)

BMI: Body mass index; COPD: Chronic obstructive pulmonary disease; MRSA: Methicillin-resistant Staphylococcus aureus.

Table 2 Perioperative data: Mesh/defect dimensions and operative technique, n (%)

	Value
Surgical approach
Open	3 (10.7)
Laparoscopic	15 (53.6)
Robotic	10 (35.7)
Implant location
Sublay	23 (82.1)
IPOM	5 (17.9)
Matrix
OviTex 1S®	5 (17.9)
OviTex LPR®	23 (82.1)
Duration of surgery	85.7 min ± 40.9 min
Defect dimensions
Length	7.5 cm ± 3.9 cm
Width	6.9 cm ± 3.4 cm
Mesh dimensions (cm × cm)
9 × 9	20 (71.4)
10 × 12	2 (7.1)
16 × 20	4 (14.3)
20 × 20	2 (7.1)
Component separation
Left myocutaneous flap	2 (7.1)
Right myocutaneous flap	18 (64.3)
Bilateral	2 (7.1)
Unspecified	1 (3.6)
None	5 (17.9)
Bowel anastomosis	23 (82.1)
Intraoperative blood transfusion	0 (0)
Concomitant procedure(s)	0 (0)
Drains placed
At least one	24 (85.7)
None	4 (14.3)
Drain locations
Abdominal wall	0 (0)
Subcutaneous	23 (82.1)
Retromuscular	3 (10.7)
Skin closure	3 (10.7)
Vacuum-assisted closure device	0 (0)

Table 3 Postoperative data: Primary and secondary study endpoints

Item	1 month	1 yr
Number of patients	28	28
Primary endpoint
Hernia recurrence	0 (0)	0 (0)
Secondary endpoints
Length of stay	2.1 d ± 1.2 d	NA
Return to work	8.3 d ± 3.0 d	NA
Readmission	3 (10.7)	0 (0)
Wound	0 (0)	0 (0)
Mesh infection	2 (7.1)	0 (0)
Gastrointestinal	2 (7.1)	0 (0)
Surgical site infection
Superficial	0 (0)	NA
Deep	0 (0)	NA
Seroma	0 (0)	0 (0)
Hematoma	0 (0)	NA
Wound dehiscence	0 (0)	NA
Fistula	2 (7.1)	0 (0)
Mechanical obstruction	0 (0)	0 (0)
Mesh infection	2 (7.1)	0 (0)
Mesh removal	1 (3.6)	0 (0)

NA: Not available.