Post-operative abdominal complications in Crohn’s disease in the biological era: Systematic review and meta-analysis

Table 2 Studies showing primary and secondary outcome measures

Ref.	Follow-up (d)	Anastomotic leak (%)	Abdominal sepsis (%)	Wound sepsis (%)	Total infectious complications (%)	Re-operation(%)	Mortality(%)
Appau et al[7]
Infliximab	30	10	10	0	40	8	1.6
No infliximab		4.2	4.3	0.3	21.5	3	0
Canedo et al[10]
Infliximab	30	5.7	3.1	13.8	21.5	3	NS
No infliximab		4.9	5	8.8	18.8	6	NS
Colombel et al[11]
Infliximab	30	NS	NS	NS	17.3	NS	0
No infliximab		NS	NS	NS	37	NS	0
El Hussuna et al[17]
Infliximab	30	9.4	NS	NS	NS	NS	1.35
No infliximab		12.7	NS	NS	NS	NS
Kasparek et al[15]
Infliximab	30	8.3	6.2	18.8	56.2	23	2.1
No infliximab		12.5	10.4	14.6	41.6	21	0
Kotze et al[23]	30
Infliximab		NS	10.5	NS	NS	NS	0
No infliximab		NS	15.8	NS	NS	NS	3
Marchal et al[18]
Infliximab	90	0	12.5	5	25	0	0
No infliximab		5.8	10.3	2.5	12.8	0	0
Mascarenhas et al[16]
Inflixmab	30	10.5	NS	10.5	NS	NS	0
No infliximab		4.1	NS	4.1	NS	NS	0
Myrelid et al[21]
Infliximab	30	7.2	NS	NS	23.4	8	NS
No infliximab		8	NS	NS	22	7	NS
Nasir et al[20]
Infliximab	30	3.4	NS	NS	NS	NS	0
No infliximab		2	NS	NS	NS	NS	0.79
Nørgård et al[9]
Infliximab	30	3.7	NS	NS	NS	7	0.46
No infliximab		2.7	NS	NS	NS	8	2.59
Syed et al[8]
Infliximab	NS	3.3	18.7	18.7	36	16	1.3
No infliximab		3.4	15.4	11.4	25	13	0.57
Tay et al[19]
Infliximab	30	4.5	9.1	NS	13.6	NS	NS
No infliximab		5.1	5.1	NS	10.2	NS	NS
Uchino et al[22]
Infliximab	30	NS	5.1	1.3	NS	NS	NS
No infliximab		NS	5.2	15.33	NS	NS	NS

NS: Not stated.