Published online Mar 27, 2016. doi: 10.4240/wjgs.v8.i3.193
Peer-review started: September 17, 2015
First decision: October 30, 2015
Revised: December 17, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: March 27, 2016
Core tip: Inflammatory bowel diseases (IBDs) are chronic conditions, requiring life-long therapy and monitoring. Surgery is not curative and the disease might recur after operation as post-operative recurrence in Crohn’s disease patients and pouchitis in ulcerative colitis patients. In both cases, endoscopy with histology is the gold standard procedure to assess disease activity. Non-invasive markers of intestinal inflammation, such as fecal calprotectin and lactoferrin, might be useful in the post-operative management of IBD patients, in order to identify individuals requiring endoscopy, so that they can avoid unnecessary invasive investigations. This paper reviews the current knowledge on the use of fecal markers in this specific setting.