Published online Feb 27, 2016. doi: 10.4240/wjgs.v8.i2.115
Peer-review started: August 1, 2015
First decision: November 6, 2015
Revised: November 15, 2015
Accepted: December 8, 2015
Article in press: December 11, 2015
Published online: February 27, 2016
Core tip: Inflammatory bowel disease (IBD) is a chronic illness with a paucity of safe and effective treatments, either medically or surgically. The aryl hydrocarbon receptor represents a novel target for future treatments of IBD using dietary ligands of the receptor. Many studies have examined the interplay between the aryl hydrocarbon receptor and gastrointestinal mucosal immunity, though there remains a gap in the understanding of how dietary ligands can modulate this activity. Our objective was to highlight elements of current literature focusing on aryl hydrocarbon receptor biology, IBD, and how their interplay can be activated with dietary “micronutriceuticals”.