Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Sep 27, 2026; 18(9): 122362
Published online Sep 27, 2026. doi: 10.4240/wjgs.122362
Published online Sep 27, 2026. doi: 10.4240/wjgs.122362
Association between central venous pressure and postoperative pulmonary complications in living-donor liver transplantation for pediatric patients
Ai-Li Dong, Hong-Xia Li, Department of Anesthesiology, First Central Hospital of Tianjin Medical University, Tianjin 300192, China
Li-Li Jia, Ying Sun, Wen-Li Yu, Department of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China
Wei Gao, Department of Hepatic Transplantation, Tianjin Key Laboratory of Organ Transplantation, Tianjin 300192, China
Author contributions: Dong AL and Li HX contributed equally to all aspects of this manuscript including study conception and design, data acquisition, analysis, and interpretation, and drafting of the article; Jia LL and Sun Y contributed to study conception and design, data analysis and interpretation, and drafting of the article; Gao W contributed to data acquisition; and Yu WL supervised the research and approved the final draft.
AI contribution statement: Portions of this manuscript were edited using AI tools solely for language refinement. The authors carefully reviewed and verified all AI-assisted outputs and take full responsibility for the scientific content of the manuscript.
Supported by Tianjin Horizontal Research Project, No. YLGX-MZ-2022008; Tianjin Key Clinical Speciality (Anaesthesiology) Construction Project; and Tianjin Key Medical Construction Project, No. TJYXZDXK-3-022C.
Institutional review board statement: This retrospective study was approved by the Institutional Review Board of First Central Hospital of Tianjin Medical University No. KYAP2025-153.
Informed consent statement: The need for patient consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Wen-Li Yu, PhD, Chief Physician, Department of Anesthesiology, Tianjin First Central Hospital, No. 24 Fukuang Road, Nankai District, Tianjin 300192, China. yzxwenliyu@163.com
Received: April 20, 2026
Revised: June 30, 2026
Accepted: August 25, 2026
Published online: September 27, 2026
Processing time: 151 Days and 11.1 Hours
Revised: June 30, 2026
Accepted: August 25, 2026
Published online: September 27, 2026
Processing time: 151 Days and 11.1 Hours
Core Tip
Core Tip: This retrospective study identified a novel J-shaped association between intraoperative central venous pressure (CVP) and postoperative pulmonary complications (PPCs) in 426 pediatric living-donor liver transplant recipients. Multivariate analysis demonstrated that each 1-unit increase in CVP was associated with a 9% reduction in PPC risk [odds ratio (OR) = 0.91, 95% confidence interval: 0.85-0.97, P = 0.007], with the strongest association observed at CVP < 9.3 cmH2O (OR = 0.834, P = 0.0006). These findings may provide insight into CVP as a modifiable factor for PPC mitigation in pediatric transplantation.