Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Sep 27, 2026; 18(9): 119606
Published online Sep 27, 2026. doi: 10.4240/wjgs.119606
Published online Sep 27, 2026. doi: 10.4240/wjgs.119606
Traditional Chinese medicines in regulating gut microbiome: Mechanisms and therapeutic applications
Zhuo Fu, School of Basic Medical Sciences, Inner Mongolia Minzu University, Tongliao 028000, Inner Mongolia Autonomous Region, China
Author contributions: Fu Z contributed to design and write of the manuscript.
AI contribution statement: During the preparation of this work, the authors used DeepSeek solely for language polishing and writing assistance. The AI tool was not used to generate research ideas, data analysis, study design, result interpretation, or any figures/images. All intellectual content, opinions, arguments, and conclusions are the original work of the authors. After using DeepSeek, the authors reviewed and edited the content as needed and take full responsibility for the final manuscript.
Supported by the First-Class Discipline Research Project of the Department of Education of Inner Mongolia Autonomous Region, No. YLXKZX-NMD-008; and the Research Initiation Project of Science and Technology Department of Inner Mongolia Minzu University, No. KYQD23014.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Zhuo Fu, PhD, Lecturer, School of Basic Medical Sciences, Inner Mongolia Minzu University, No. 996 Xilamulun Street, Tongliao 028000, Inner Mongolia Autonomous Region, China. fzwork@126.com
Received: February 2, 2026
Revised: April 15, 2026
Accepted: May 26, 2026
Published online: September 27, 2026
Processing time: 226 Days and 22.4 Hours
Revised: April 15, 2026
Accepted: May 26, 2026
Published online: September 27, 2026
Processing time: 226 Days and 22.4 Hours
Core Tip
Core Tip: The gut microbiome plays a crucial role in regulating physiological homeostasis and the development of diseases. This review explores the recent advancements and ongoing debates regarding the impact of Traditional Chinese Medicines on gut microbial communities, and delineates future research directions for addressing diseases associated with gut microbial dysbiosis.