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World J Gastrointest Surg. Sep 27, 2026; 18(9): 119258
Published online Sep 27, 2026. doi: 10.4240/wjgs.119258
Published online Sep 27, 2026. doi: 10.4240/wjgs.119258
Effects of perioperative early enteral nutrition and glycemic control in patients with diabetes mellitus complicated with gastric cancer
Li-Yan Zhang, Department of CDC, The 964th Hospital of PLA Joint Logistic Support Force, Changchun 130062, Jilin Province, China
Li-Chun Duan, Department of Dietary, The 964th Hospital of PLA Joint Logistic Support Force, Changchun 130062, Jilin Province, China
Ming-Fang Xue, Department of Dietary, Jilin Province FAW General Hospital, Changchun 130011, Jilin Province, China
Chun-Yan Lang, Department of Endocrinology, The 964th Hospital of PLA Joint Logistic Support Force, Changchun 130062, Jilin Province, China
Co-first authors: Li-Yan Zhang and Li-Chun Duan.
Author contributions: Zhang LY and Duan LC designed the research and wrote the first manuscript, they contributed equally to this article, they are the co-first authors of this manuscript; Zhang LY, Duan LC, and Xue MF contributed to conceiving the research and analyzing data; Zhang LY, Duan LC, and Lang CY conducted the analysis and provided guidance for the research; and all authors reviewed and approved the final manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the 964th Hospital of PLA Joint Logistic Support Force, approval No. Y-20260414-005.
Informed consent statement: The requirement for written informed consent was waived due to retrospective design of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Chun-Yan Lang, Associate Chief Physician, Department of Endocrinology, The 964th Hospital of PLA Joint Logistic Support Force, No. 4799 Xian Road, Lvyuan District, Changchun 130062, Jilin Province, China. alzccvbnm@163.com
Received: April 10, 2026
Revised: May 19, 2026
Accepted: July 1, 2026
Published online: September 27, 2026
Processing time: 157 Days and 23.4 Hours
Revised: May 19, 2026
Accepted: July 1, 2026
Published online: September 27, 2026
Processing time: 157 Days and 23.4 Hours
Core Tip
Core Tip: This non-randomized retrospective cohort study analyzed the effects of perioperative early enteral nutrition (EEN) combined with glycemic control in patients with type 2 diabetes mellitus complicated with gastric cancer, using EEN combined with standard glycemic control serving as the control intervention. Comparative analyses demonstrated that perioperative EEN combined with intensive glycemic control was more effective than EEN combined with standard glycemic control. Specifically, the former intervention more effectively controlled blood glucose, improved nutritional status and humoral immune function, and promoted early recovery without increasing the overall incidence of complications.