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World J Gastrointest Surg. Nov 27, 2026; 18(11): 124761
Published online Nov 27, 2026. doi: 10.4240/wjgs.124761
Published online Nov 27, 2026. doi: 10.4240/wjgs.124761
Gastric metastasis from renal cell carcinoma with a 10-year interval: A case report
Tian-Zhe Gao, Chi-Yu He, Yu-Ming Lou, Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Chao-Ze Zheng, Kan-Kai Zhu, Xing-Nan Wu, Xiao-Sun Liu, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Author contributions: Gao TZ contributed to writing - original draft; Zhu KK contributed to resources, writing - review and editing; Wu XN contributed to data curation; Gao TZ and Zheng CZ contributed to investigation; He CY contributed to funding acquisition; Lou YM contributed to methodology; Liu XS contributed to conceptualization; and all authors have read and approved the final manuscript.
AI contribution statement: Portions of this manuscript were edited using AI tools solely for language refinement. The authors carefully reviewed and verified all AI-assisted outputs and take full responsibility for the scientific content of the manuscript.
Supported by the Key Research & Development Plan of Zhejiang Province, No. 2025C02171.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Xiao-Sun Liu, PhD, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 366 Wutong Road, Hangzhou 310000, Zhejiang Province, China. xiaosunliu@zju.edu.cn
Received: June 24, 2026
Revised: August 3, 2026
Accepted: September 9, 2026
Published online: November 27, 2026
Processing time: 141 Days and 20.5 Hours
Revised: August 3, 2026
Accepted: September 9, 2026
Published online: November 27, 2026
Processing time: 141 Days and 20.5 Hours
Core Tip
Core Tip: Gastric metastasis from renal cell carcinoma is exceedingly rare, with a median latency of 7-10 years after nephrectomy, making it prone to diagnostic oversight. We report a 70-year-old man who developed gastric fundus metastasis 10 years after radical nephrectomy for clear cell renal cell carcinoma. Despite a suspicious computed tomography finding misread as food residue three months earlier, the lesion was confirmed by endoscopic biopsy and resected via robot-assisted wedge gastrectomy. This case underscores that even without gastrointestinal symptoms, gastric metastasis must remain on the differential for advanced renal cell carcinoma patients with prior distant metastases.