Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Nov 27, 2026; 18(11): 124443
Published online Nov 27, 2026. doi: 10.4240/wjgs.124443
Published online Nov 27, 2026. doi: 10.4240/wjgs.124443
Preventive strategies for post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis
Xiao-Yan Wang, Yan-Feng Zhang, Xiao-Qin Zhou, Department of Interventional Radiology, Eastern Hepatobiliary Surgery Hospital, Shanghai 201805, China
Yi-Yi Liu, Department of Gastroenterology, Eastern Hepatobiliary Surgery Hospital, Shanghai 201805, China
Meng-Chen Sun, Department of Hepatobiliary and Pancreatic Surgery, Shanghai East Hospital, Shanghai 200120, China
Qin Zheng, Department of Nursing, Eastern Hepatobiliary Surgery Hospital, Shanghai 201805, China
Co-first authors: Xiao-Yan Wang and Yi-Yi Liu.
Co-corresponding authors: Meng-Chen Sun and Qin Zheng.
Author contributions: Wang XY and Liu YY contributed to the conceptualization of the study, study design, literature search, study selection, and data extraction; both authors contributed equally to this article and are the co-first authors of this manuscript; Wang XY performed statistical analysis and data interpretation; Liu YY conducted risk-of-bias assessment and Grading of Recommendations Assessment, Development and Evaluation evidence evaluation; Zhang YF and Zhou XQ undertook drafting of the original manuscript as well as table and figure preparation and manuscript formatting; Sun MC and Zheng Q were responsible for critical revision of the manuscript for important intellectual content, supervision, and final approval of the version to be published, both contributed equally to this article, and are the co-corresponding authors of this manuscript; all authors read and approved the final manuscript.
AI contribution statement: During the preparation of this manuscript, AI-assisted language editing tools (including large language models such as ChatGPT and DeepSeek) were used solely for preliminary grammar correction, syntactic refinement, and vocabulary enhancement to improve the readability of the text. Following this initial AI-assisted editing, the entire manuscript underwent comprehensive professional language polishing by a certified commercial English-language editing service (certificate of editing is available upon request). Crucially, no AI tools or software were used to generate original scientific data, perform statistical analyses, conduct the systematic literature search, extract study data, interpret the pooled results, or draw any scientific conclusions. All AI-assisted outputs, as well as the final edited version, were rigorously reviewed, fact-checked, and approved by all authors. The authors assume full responsibility and accountability for the integrity, accuracy, originality, and scientific validity of all content presented in this manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Qin Zheng, Associate Chief Nurse, Department of Nursing, Eastern Hepatobiliary Surgery Hospital, No. 700 Mobei North Road, Jiading District, Shanghai 201805, China. sui0743@sina.com
Received: July 8, 2026
Revised: August 6, 2026
Accepted: October 9, 2026
Published online: November 27, 2026
Processing time: 146 Days and 21.3 Hours
Revised: August 6, 2026
Accepted: October 9, 2026
Published online: November 27, 2026
Processing time: 146 Days and 21.3 Hours
Core Tip
Core Tip: Preventive strategies, primarily non-steroidal anti-inflammatory drug-based pharmacological prophylaxis and pancreatic duct stenting, reduce the risk of post-ERCP pancreatitis by 62% (risk ratio = 0.38, 95% confidence interval: 0.30-0.48). Structured perioperative nursing pathways integrating risk screening, timely prophylaxis coordination, close postprocedural monitoring, and patient education are essential to translate this evidence into consistent clinical practice and improved patient safety.