World J Gastrointest Surg. Nov 27, 2026; 18(11): 122260 Published online Nov 27, 2026. doi: 10.4240/wjgs.122260
Enhanced recovery after surgery, based perioperative bundle reduces 30-day unplanned readmission after laparoscopic colorectal cancer surgery
Hui-Ying Li, Xiang Rao, Xin-Yang Zhou
Hui-Ying Li, Xiang Rao, Infusion Room, Wuyi Branch, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Jinhua 321200, Zhejiang Province, China
Xin-Yang Zhou, Department of Gastrointestinal Surgery, Wuyi Branch, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Jinhua 321200, Zhejiang Province, China
Author contributions: Zhou XY conceived and designed the study; Li HY and Xiang Rao collected and assembled the clinical data; Zhou XY performed the statistical analysis and interpreted the results; Li HY drafted the manuscript; Rao X and Zhou XY critically revised the manuscript for important intellectual content; all authors read and approved the final version of the manuscript.
AI contribution statement: The authors declare that no AI tools were used in the preparation of this manuscript, including study design, data collection, data analysis, interpretation of results, manuscript writing, or language editing. The authors assume full responsibility and accountability for the integrity, accuracy, originality, and scientific validity of the manuscript and all submitted materials.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Wuyi Branch, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine (approval No. WY20220712).
Informed consent statement: The requirement for informed consent was waived by the Ethics Committee of Wuyi Branch, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine because this was a retrospective study using anonymized medical records.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest to disclose.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author upon reasonable request.
Corresponding author: Xin-Yang Zhou, Department of Gastrointestinal Surgery, Wuyi Branch, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 2 Nanmen Street, Shuxi Subdistrict, Jinhua 321200, Zhejiang Province, China. 13085676071@163.com
Received: June 5, 2026 Revised: July 9, 2026 Accepted: July 28, 2026 Published online: November 27, 2026 Processing time: 159 Days and 18.1 Hours
Core Tip
Core Tip: This study evaluated the impact of a comprehensive perioperative management bundle based on an enhanced recovery after surgery (ERAS) pathway on 30-day unplanned readmission rates following laparoscopic radical resection for colorectal cancer (CRC). The intervention group (n = 39) had a significantly lower 30-day unplanned readmission rate compared with the conventional care group (per protocol, n = 38), 5.1 percent vs 23.7 percent, P = 0.024 among 77 patients. The ERAS bundle which included early mobilization, multimodal pain control, early enteral feeding, abdominal massage, psychological support as well as formalized discharge planning significantly accelerated recovery of gastrointestinal function and significantly reduced postoperative pain scores at all time points whilst improving exercise tolerance and activities of daily living along with improved quality of life overall at 30 postoperative days. These results suggest that the clinical benefits of ERAS are attributable to its synergistic multi-component bundles instead of individual interventions. The program provides a practical evidence-based approach to perioperative care that should be more broadly implemented in CRC surgical units.
