Mechanism and treatment of pancreatic duct stones

doi:10.4240/wjgs.v17.i8.108312

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Aug 27, 2025 (publication date) through Aug 28, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Aug 27, 2025; 17(8): 108312
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.108312

Mechanism and treatment of pancreatic duct stones

Sheng Wu, Ye Zheng, Jiang-Wei Mou, Yan-Jun Zhang, Ke-Xiang Zhu

Sheng Wu, Ye Zheng, Jiang-Wei Mou, Yan-Jun Zhang, Ke-Xiang Zhu, The First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China

Ke-Xiang Zhu, Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China

Author contributions: Wu S wrote the main manuscript text; Zheng Y, Mou JW, and Zhang YJ revised the format, structure and important thesis of the paper; Zhu KX gave guidance and reviewed the content of the final draft; and all authors reviewed the manuscript.

Supported by the National Natural Science Foundation of Gansu province, No. 22JR11RA023.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Ke-Xiang Zhu, MD, PhD, Associate Professor, Chief Physician, Department of General Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. flexzhu6910@163.com

Received: April 23, 2025
Revised: May 29, 2025
Accepted: July 11, 2025
Published online: August 27, 2025
Processing time: 125 Days and 0.8 Hours

Core Tip

Core Tip: Pancreatic duct stones represent a complication associated with chronic pancreatitis. This review highlights recent progress in understanding the pathophysiology and management of pancreatic duct stones. The emerging evidence contributes to a more nuanced understanding of their formation and informs contemporary clinical treatment strategies. The findings offer valuable relevance to the field of gastroenterology, especially in the context of chronic pancreatitis.