Meta-Analysis
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 107706
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.107706
Kamikawa anastomosis in proximal gastrectomy for gastric cancer: A systematic review and meta-analysis
Cheng-Cong Liu, Jian Yang, Gang Yin, Zhen Tian, Chen Qin
Cheng-Cong Liu, Department of Gastrointestinal Surgery, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266000, Shandong Province, China
Jian Yang, Department of General Surgery, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266000, Shandong Province, China
Gang Yin, Department of Blood Transfusion, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266000, Shandong Province, China
Zhen Tian, Medical School, Nanjing University, Nanjing 266000, Jiangsu Province, China
Chen Qin, Department of Oncology, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao 266000, Shandong Province, China
Author contributions: Liu CC, Yang J, Yin G, Tian Z, and Qin C designed the research; Liu CC and Yang J were responsible for data acquisition, analysis, and interpretation; Liu CC wrote the paper; Yang J, Yin G, Tian Z, and Qin C reviewed the manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chen Qin, MD, Department of Oncology, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, No. 127 Siliu South Road, Qingdao 266000, Shandong Province, China. qinchenqinchen123@126.com
Received: March 28, 2025
Revised: May 22, 2025
Accepted: July 2, 2025
Published online: August 27, 2025
Processing time: 150 Days and 22.4 Hours
Core Tip

Core Tip: This systematic review and meta-analysis evaluates the efficacy, safety, and nutritional outcomes of Kamikawa anastomosis following proximal gastrectomy for gastric cancer. Our findings suggest that Kamikawa anastomosis offers favorable anti-reflux benefits with a low incidence of anastomotic complications, including leakage and stenosis. The procedure is associated with acceptable postoperative outcomes, although it requires longer operative times compared to total gastrectomy. Despite some nutritional loss, the overall clinical profile supports its viability as an option for proximal gastrectomy, addressing a significant gap in surgical decision-making for gastric cancer.