Observational Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 107209
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.107209
Prevalence of sarcopenia in patients with surgical obstructive jaundice and its impact on clinical outcomes
Run-Nan Zhang, Jian-Yong Cui, Zhong-Hua Zhao, Ya-Tong Li, Zhi-Wei Liu, Ji-Yue Zhang, Qiang Wei, Yan-Min Lu, Qiang-Pu Chen
Run-Nan Zhang, Jian-Yong Cui, Yan-Min Lu, Department of Clinical Nutrition, Binzhou Medical University Hospital, Binzhou 256603, Shandong Province, China
Zhong-Hua Zhao, Ya-Tong Li, Zhi-Wei Liu, Ji-Yue Zhang, Qiang Wei, Qiang-Pu Chen, Department of Hepatobiliary-Pancreatic Surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong Province, China
Co-first authors: Run-Nan Zhang and Jian-Yong Cui.
Author contributions: Zhang RN and Cui JY conducted data curation, methodology, software, validation, writing-original draft and editing; Zhao ZH, Li YT contributed data curation, writing-review and editing; Liu ZW, Zhang JY, Wei Q contributed writing-review and editing; Lu YM contributed writing-review and editing; Chen QP conducted conceptualization, supervision, writing-review and editing. Zhang RN and Cui JY have made crucial and indispensable contributions towards the completion of the project and thus qualified as the co-first authors of the paper.
Supported by Shandong Province Biliary Pancreatic Cancer Clinical Quality Specialty Construction Fund, No. SLCZDZK-2401.
Institutional review board statement: The research protocol adhered to every provision of the Helsinki Declaration and received approval from the Research Ethics Committee of the Binzhou Medical University Hospital (Approval No. KYLL-264).
Informed consent statement: Since this research project was conducted on the basis of patients' routine treatment surgeries, without any additional procedures and without causing harm to the patients' bodies, we adopted the waiver of informed consent in the clinical setting.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiang-Pu Chen, Chief Physician, Professor, Department of Hepatobiliary-Pancreatic Surgery, Binzhou Medical University Hospital, No. 661 Huang He Er Road, Binzhou 256603, Shandong Province, China. drchenqiangpu@163.com
Received: March 18, 2025
Revised: May 31, 2025
Accepted: July 11, 2025
Published online: August 27, 2025
Processing time: 160 Days and 18.6 Hours
Core Tip

Core Tip: Atrophy of muscles adversely affects surgical treatment and prognosis for patients. As a result, sarcopenia has been receiving increasing attention. The occurrence of sarcopenia associated with hepatobiliary and pancreatic surgical diseases is influenced by various factors. Obstructive jaundice is a common symptom in patients with these diseases; however, few studies have investigated its effects on muscle function. Therefore, this study analyzed obstructive jaundice-related sarcopenia from different perspectives, aiming to provide theoretical support for understanding this condition.