Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 105990
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.105990
Ultrasound-guided quadratus lumborum block with general anesthesia for perioperative circulatory stability in colorectal cancer surgery
Hui-Jie Li, Xi Ban, Jing Li, Su-Qin Huang
Hui-Jie Li, Xi Ban, Jing Li, Department of Anesthesiology, Shulan (Quzhou) Hospital, Quzhou 324000, Zhejiang Province, China
Su-Qin Huang, Department of Anesthesiology, Zhejiang Shuren University Shulan International Medical College Affiliated Shulan (Hangzhou) Hospital, Hangzhou 310000, Zhejiang Province, China
Author contributions: Li HJ conceptualized this study; Ban X contributed to data collection; Li HJ and Huang SQ jointly drafted the initial draft and contributed to the formal analysis; Li J provided guidance and contributed to the methodology and visualization of this study; Li HJ, Ban X, and Huang SQ jointly validated this study and edited the entire content of the manuscript.
Institutional review board statement: This study has been reviewed and approved by the Ethics Review Committee of Shulan (Quzhou) Hospital (No. SLYL-2023-219).
Informed consent statement: This study was approved by the patients or their guardians.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No available data.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Su-Qin Huang, MD, Chief Physician, Department of Anesthesiology, Zhejiang Shuren University Shulan International Medical College Affiliated Shulan (Hangzhou) Hospital, No. 848 Dongxin Road, Hangzhou 310000, Zhejiang Province, China. suqin.huang@shulan.com
Received: April 30, 2025
Revised: May 29, 2025
Accepted: June 23, 2025
Published online: August 27, 2025
Processing time: 116 Days and 17.7 Hours
Core Tip

Core Tip: This retrospective study demonstrates that ultrasound-guided quadratus lumborum block (QLB) combined with general anesthesia significantly improves perioperative outcomes in colorectal cancer surgery. Compared to general anesthesia alone, QLB reduces stress markers (glucose, lactic acid), enhances renal function (blood urea nitrogen, creatinine), and lowers postoperative pain scores. These findings support the use of QLB as a superior anesthetic strategy to maintain circulatory and metabolic stability, protect organ function, and improve recovery. QLB is especially beneficial for patients with renal vulnerability, high stress reactivity, or low pain tolerance, offering safer and more effective perioperative management.