Anastomotic leak after ileocolic resection for Crohn’s disease: The latest evidence

doi:10.4240/wjgs.v17.i7.100766

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Jul 27, 2025 (publication date) through Jul 26, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jul 27, 2025; 17(7): 100766
Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.100766

Anastomotic leak after ileocolic resection for Crohn’s disease: The latest evidence

Miao-Lin Lei, Li-Li Dong, Yan-Bo Yu

Miao-Lin Lei, Yan-Bo Yu, Department of Gastroenterology, Laboratory of Translational Gastroenterology, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China

Li-Li Dong, Department of Gastroenterology, Affiliated Qingdao Third People’s Hospital, Qingdao University, Qingdao 266001, Shandong Province, China

Author contributions: Lei ML performed the bibliographic search; Lei ML and Dong LL designed the overall concept and outline of the manuscript; Yu YB revised the article critically for important intellectual content; and all authors approved the final version of the manuscript.

Supported by National Natural Science Foundation of China, No. NSFC 82070540; the Taishan Scholars Program of Shandong Province, No. tsqn202211309; and ECCM Program of Clinical Research Center of Shandong University, No. 2021SDUCRCB003.

Conflict-of-interest statement: The authors certify that they have no conflicts of interest related to this work.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Yan-Bo Yu, MD, PhD, Doctor, Professor, Department of Gastroenterology, Laboratory of Translational Gastroenterology, Qilu Hospital, Shandong University, No. 107 Wenhuaxi Road, Jinan 250012, Shandong Province, China. yuyanbo2000@126.com

Received: August 26, 2024
Revised: March 8, 2025
Accepted: March 24, 2025
Published online: July 27, 2025
Processing time: 331 Days and 20.6 Hours

Core Tip

Core Tip: Anastomotic leak (AL) frequently occurs as a complication following ileocolic resection. Early warning of its high-risk factors facilitates the adoption of effective, targeted strategies to mitigate the occurrence of AL and optimize surgical quality. The prevention of AL plays a crucial role in the postoperative management of Crohn's disease, contributing significantly to patient outcomes.