Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2024; 16(1): 67-75
Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.67
Impact of open hepatectomy on postoperative bile leakage in patients with biliary tract cancer
Gang Wu, Wen-Ying Li, Yu-Xing Gong, Feng Lin, Chen Sun
Gang Wu, Wen-Ying Li, Yu-Xing Gong, Feng Lin, Chen Sun, General Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China
Author contributions: Wu G and Sun C proposed the concept of this study; Li WY contributed to data collection; Wu G and Gong YX drafted the first draft; Lin F contributed to the formal analysis of this study; Sun C conducted guidance research, methodology, and visualization; all authors participated in the study, validated the study, and jointly reviewed and edited the manuscript.
Institutional review board statement: This study has been approved by the Clinical Research Project Ethics Review of the Medical Ethics Committee of the Second Affiliated Hospital of Harbin Medical University, with the Ethics Review Approval Document (No. KY2023-111).
Informed consent statement: All study participants or their legal guardians provided written informed consent before study enrollment.
Conflict-of-interest statement: All authors declare that there are no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chen Sun, MD, Associate Chief Physician, General Surgery Department, The Second Affiliated Hospital of Harbin Medical University, No. 196 Jiankang Road, Nangang District, Harbin 150000, Heilongjiang Province, China. acu23456@163.com
Received: October 26, 2023
Peer-review started: October 26, 2023
First decision: November 8, 2023
Revised: November 9, 2023
Accepted: December 20, 2023
Article in press: December 20, 2023
Published online: January 27, 2024
Core Tip

Core Tip: Bile leakage is a common complication of open hepatectomy for biliary tract cancer; however, it can be managed conservatively in most cases. The incidence of bile leak was 16.7% and was primarily grade A according to the liver surgery classification. The most common site was the cut surface of the liver. Treatment involved conservative measures such as drainage and antibiotics, with some cases requiring endoscopic or percutaneous intervention. Male sex, hepatocellular carcinoma, major hepatectomy, blood loss, and blood transfusion were identified as risk factors for bile leakage. Awareness of these factors can help optimize management strategies and reduce the occurrence of bile leaks.