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World J Gastrointest Surg. May 27, 2023; 15(5): 757-775
Published online May 27, 2023. doi: 10.4240/wjgs.v15.i5.757
Application of indocyanine green in surgery: A review of current evidence and implementation in trauma patients
Husham Abdelrahman, Ayman El-Menyar, Ruben Peralta, Hassan Al-Thani
Husham Abdelrahman, Ruben Peralta, Trauma Surgery, Hamad Medical Corporation, Doha 3050, Qatar
Ayman El-Menyar, Hassan Al-Thani, Trauma and Vascular Surgery, Hamad Medical Corporation, Doha 3050, Qatar
Author contributions: Abdelrahman H, El-Menyar A, Peralta R, and Al-Thani H contributed to the manuscript in terms of substantial contributions to conception and design of the study, acquisition of data, or analysis and interpretation of data; drafting the article or making critical revisions related to important intellectual content of the manuscript; all authors contributed to final approval of the version of the article to be published.
Conflict-of-interest statement: There are no conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Ayman El-Menyar, FACC, FESC, FRCP, MBChB, MSc, Associate Professor, Director, Senior Scientist, Trauma and Vascular Surgery, Hamad Medical Corporation, Al Rayyan Road, Doha 3050, Qatar.
Received: December 17, 2022
Peer-review started: December 17, 2022
First decision: January 3, 2023
Revised: January 18, 2023
Accepted: March 27, 2023
Article in press: March 27, 2023
Published online: May 27, 2023
Core Tip

Core Tip: There is no consensus on the ideal dose, time, and manner of administration of Indocyanine green Fluorescence (ICG) as well as its indications in the acute surgical settings. There is a scarcity of publications describing the use of ICG in trauma patients as a useful adjunct to facilitate intraoperative decisions and to safely limit the extent of surgical resection. ICG has been increasingly used for surgical guidance as an intraoperative localizing technique, tissue perfusion evaluation, and imaging for anatomy identification and leaks as well as to provide targeted therapies. This review explored the potential utility of ICG in trauma surgery.