Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jul 27, 2022; 14(7): 656-669
Published online Jul 27, 2022. doi: 10.4240/wjgs.v14.i7.656
Adult patients with allied disorders of Hirschsprung’s disease in emergency department: An 11-year retrospective study
Shuai Jiang, Cong-Ying Song, Meng-Xiao Feng, Yuan-Qiang Lu
Shuai Jiang, Cong-Ying Song, Meng-Xiao Feng, Yuan-Qiang Lu, Department of Emergency Medicine, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Shuai Jiang, Cong-Ying Song, Meng-Xiao Feng, Yuan-Qiang Lu, Key Laboratory for Diagnosis and Treatment of Aging and Physic-chemical Injury Diseases of Zhejiang Province, Hangzhou 310003, Zhejiang Province, China
Author contributions: Jiang S and Lu YQ conceived and designed the study; Jiang S and Feng MX collected the clinical data; Jiang S and Song CY provided statistical advice on study design and analyzed the data; Jiang S drafted the manuscript; and all authors contributed substantially to manuscript revision; Lu YQ takes responsibility for the paper as a whole.
Supported by the Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine, No. 2017-XK-A36.
Institutional review board statement: This study was approved by the Ethics Committee of the First Affiliated Hospital, Zhejiang University School of Medicine (No. 2021271).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Yuan-Qiang Lu, MD, PhD, Professor, Department of Emergency Medicine, The First Affiliated Hospital, School of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China.
Received: August 17, 2021
Peer-review started: August 17, 2021
First decision: September 12, 2021
Revised: September 21, 2021
Accepted: June 24, 2022
Article in press: June 24, 2022
Published online: July 27, 2022
Core Tip

Core Tip: Emergency physicians should be vigilant regarding patients with chronic constipation, abdominal pain, or abdominal distension, especially those with recurrent and intolerable symptoms. Allied disorders of Hirschsprung’s disease (ADHD) should be considered in such cases despite its rarity. Abdominal computed tomography examination is recommended as a useful tool to make a suspected diagnosis of ADHD. Clinicians should also be wary of uncommon symptoms and false-negative imaging findings. Body mass index, cholinesterase, and blood chlorine have good discriminative abilities between ADHD and irritable bowel syndrome. The nutritional status of adult patients with ADHD is worthy of further attention.