Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2022; 14(12): 1350-1362
Published online Dec 27, 2022. doi: 10.4240/wjgs.v14.i12.1350
Low preoperative skeletal muscle index increases the risk of mortality among resectable pancreatic cancer patients: A retrospective study
Zhi-Wei Cai, Jia-Lin Li, Meng Liu, Hong-Wei Wang, Chong-Yi Jiang
Zhi-Wei Cai, Meng Liu, Hong-Wei Wang, Chong-Yi Jiang, Department of General Surgery, Hepato-Biliary-Pancreatic Center, Huadong Hospital, Shanghai 200040, China
Jia-Lin Li, Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Author contributions: Cai ZW, Li JL, and Liu M contributed equally to this manuscript; Jiang CY participated in the conception and design of this study; Cai ZW participated in the data collection, analysis, and drafting of the article; Li JL and Liu M participated in the design of the study and data analyses; Wang HW participated in the data collection; All authors have read and approved the final manuscript.
Supported by Shanghai Science and Technology Commission of Shanghai Municipality, No. 20Y11908600; Shanghai Shenkang Hospital Development Center, No. SHDC2020CR5008; and Shanghai Municipal Health Commission, No. 20194Y0195.
Institutional review board statement: The study was reviewed and approved by the Ethics Review Committee of Huadong Hospital (Shanghai).
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chong-Yi Jiang, MD, Chief Doctor, Department of General Surgery, Hepato-Biliary-Pancreatic Center, Huadong Hospital, West No. 221 Yan’an Road, Shanghai 200040, China. jiangzhongyi9@sina.com
Received: September 16, 2022
Peer-review started: September 16, 2022
First decision: October 20, 2022
Revised: October 29, 2022
Accepted: December 6, 2022
Article in press: December 6, 2022
Published online: December 27, 2022
Core Tip

Core Tip: Measures of body composition have been regarded as a reliable prognostic predictor for cancer patients after surgery, but further research is needed. In this study, we showed that low preoperative skeletal muscle index (SMI) potentially predicts the prognosis of pancreatic cancer patients. We also revealed that low SMI was more prevalent in elderly patients and was associated with a poor prognosis among elderly patients after pancreatic cancer resection.