Opinion Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2021; 13(3): 222-230
Published online Mar 27, 2021. doi: 10.4240/wjgs.v13.i3.222
Paraesophageal hernia and iron deficiency anemia: Mechanisms, diagnostics and therapy
Christoph G Dietrich, Dolores Hübner, Joachim W Heise
Christoph G Dietrich, Department of Internal Medicine, Bethlehem Center of Health, Stolberg D-52222, Germany
Dolores Hübner, Department of Radiology, Bethlehem Center of Health, Stolberg D-52222, Germany
Joachim W Heise, Department of General and Abdominal Surgery, Bethlehem Health Center, Stolberg D-52222, Germany
Author contributions: Dietrich CG developed the concept of this review, and all authors contributed to the manuscript.
Conflict-of-interest statement: The authors declare no conflict of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Christoph G Dietrich, MD, PhD, Chief Doctor, Department of Internal Medicine, Bethlehem Center of Health, Bethlehem-Gesundheitszentrum Stolberg/Rhld, Steinfeldstr 5, Stolberg D-52222, Germany. dietrich@bethlehem.de
Received: December 30, 2020
Peer-review started: December 30, 2020
First decision: January 18, 2021
Revised: January 23, 2021
Accepted: March 10, 2021
Article in press: March 10, 2021
Published online: March 27, 2021
Core Tip

Core Tip: Large axial or paraesophageal hernias may cause iron deficiency anemia, but the detailed mechanisms, necessary diagnostic procedures and therapeutic possibilities are not completely clear and have not been standardized. This review summarizes the knowledge regarding these aspects in an often-neglected cause of anemia, especially in older patients.