Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2021; 13(10): 1180-1189
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1180
Gastric endoscopic submucosal dissection in Western countries: Indications, applications, efficacy and training perspective
Luca De Luca, Massimiliano Di Berardino, Benedetto Mangiavillano, Alessandro Repici
Luca De Luca, Massimiliano Di Berardino, Gastroenterology and Digestive Endoscopy Unit, Riuniti Marche North Hospital, Pesaro 61121, Italy
Benedetto Mangiavillano, Gastrointestinal Endoscopy Unit, Humanitas - Mater Domini, Castellanza 21053, Italy
Alessandro Repici, Digestive Endoscopy Unit, Humanitas Clinical and Research Center, Humanitas University, Rozzano 20089, Italy
Author contributions: De Luca L, Di Berardino M, Mangiavillano B and Repici A contributed equally to this work; All authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Luca De Luca, MD, Doctor, Gastroenterology and Digestive Endoscopy Unit, Riuniti Marche North Hospital, Piazzale Cinelli, 1, Pesaro 61121, Italy.
Received: May 24, 2021
Peer-review started: May 24, 2021
First decision: June 17, 2021
Revised: July 2, 2021
Accepted: August 3, 2021
Article in press: August 3, 2021
Published online: October 27, 2021
Core Tip

Core Tip: In Western countries, endoscopic submucosal dissection (ESD) is an accepted first-line therapy of superficial gastric neoplasia, including dysplastic and recurrent lesions. This technique allows a high rate of curative resection and a good safety profile compared with other therapeutic approaches, including surgery, which can be reserved as a rescue therapy. Despite there certainly being some obstacles to its diffusion in the West, European Society of Gastrointestinal Endoscopy has developed a European core curriculum for ESD practice across Europe, with the aim of high quality ESD training. Probably nowadays, Western endoscopists are slowly reaching the same level of expertise and proficiency of the colleagues from the East.