Systemic Reviews
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2020; 12(5): 247-258
Published online May 27, 2020. doi: 10.4240/wjgs.v12.i5.247
Management of synchronous lateral pelvic nodal metastasis in rectal cancer in the era of neoadjuvant chemoradiation: A systemic review
Jolene Si Min Wong, Grace Hwei Ching Tan, Claramae Shulyn Chia, Chin-Ann Johnny Ong, Melissa Ching Ching Teo
Jolene Si Min Wong, Grace Hwei Ching Tan, Claramae Shulyn Chia, Chin-Ann Johnny Ong, Melissa Ching Ching Teo, Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore
Grace Hwei Ching Tan, Claramae Shulyn Chia, Chin-Ann Johnny Ong, Melissa Ching Ching Teo, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore
Chin-Ann Johnny Ong, Laboratory of Applied Human Genetics, Division of Medical Sciences, National Cancer Centre Singapore, Singapore 169610, Singapore
Chin-Ann Johnny Ong, Institute of Molecular and Cell Biology, A*STAR Research Entities, 61 Biopolis Drive, Singapore 138673, Singapore
Author contributions: Wong JSM was involved in the collection and synthesis of all data and manuscript writing; Tan GHC oversaw the project progress and was involved in the final editing of the manuscript; Chia CS, Ong CAJ and Teo MCC was involved in the editing and reviewing of the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Grace Tan Hwei Ching, FRCS (Gen Surg), MBBS, Consultant, MMED (Surg), Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore. gracethc@gmail.com
Received: December 7, 2019
Peer-review started: December 7, 2019
First decision: December 17, 2019
Revised: March 3, 2020
Accepted: April 28, 2020
Article in press: April 28, 2020
Published online: May 27, 2020
Core Tip

Core tip: The role of lateral pelvic lymph node (LLN) dissection in rectal cancer patients with synchronous radiologically suspicious LLN is unclear in the era of neoadjuvant chemoradiation. Our systemic review aims to define the role of LLN dissection for patients with synchronous LLNs.