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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2021; 13(1): 30-49
Published online Jan 27, 2021. doi: 10.4240/wjgs.v13.i1.30
Pancreas-preserving duodenal resections vs pancreatoduodenectomy for groove pancreatitis. Should we revisit treatment algorithm for groove pancreatitis?
Vyacheslav Egorov, Roman Petrov, Aleksandr Schegolev, Elena Dubova, Andrey Vankovich, Eugeny Kondratyev, Andrey Dobriakov, Dmitry Kalinin, Natalia Schvetz, Elena Poputchikova
Vyacheslav Egorov, Roman Petrov, Department of Surgical Oncology, Ilyinskaya Hospital, Moscow 143421, Russia
Aleksandr Schegolev, V. I. Kulakov Research Center for Obstetrics, Ministry Hlth Russian Federat, VI Kulakov Res Ctr Obstet Gynecol & Perinatol, Moscow 119526, Russia
Elena Dubova, Department of Pathology, Buranazian Federal Medical and Biological Center of the Federal Medical and Biological Agency of Russian Federation, Moscow 143421, Russia
Andrey Vankovich, Department of HPB Surgery, Moscow Clinical Research Center, Moscow 111123, Russia
Eugeny Kondratyev, Department of Radiology, Vishnevsky Institute of Surgery, Ilyinskaya Hospital, Moscow 143421, Russia
Andrey Dobriakov, Natalia Schvetz, Elena Poputchikova, Department of Pathology, Bakhrushin Brothers Moscow City Hospital, Moscow 107076, Russia
Dmitry Kalinin, Department of Pathology, Vishnevsky Institute of Surgery, Ilyinskaya Hospital, Moscow 117997, Russia
Author contributions: Egorov V contributed to idea, surgery, acquisition, analysis and interpretation of data, writing the paper; Petrov R and Vankovich A contributed to surgery, acquisition, analysis and interpretation of data, paper revision; Kondratyev E contributed to acquisition, analysis and interpretation of radiological data, paper revision; Schegolev A, Dubova E, Dobriakov A, Kalinin D, Schvetz N, and Poputchikova E contributed to pathological examination, acquisition, analysis and interpretation of pathohistological data, paper revision.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Ilyinskaya Hospital, approval No. 03-01-SG/2020 of January 14, 2020.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Vyacheslav Egorov, MD, PhD, Associate Professor, Department of Surgical Oncology, Ilyinskaya Hospital, Rubliovskoye predmestiie 2-2, Moscow 143421, Russia. egorov12333@gmail.com
Received: August 3, 2020
Peer-review started: August 3, 2020
First decision: September 17, 2020
Revised: September 22, 2020
Accepted: December 2, 2020
Article in press: December 2, 2020
Published online: January 27, 2021
ARTICLE HIGHLIGHTS
Research background
Today most pancreatologists recognize groove pancreatitis as a distinct form of chronic pancreatitis, but the natural history of the disease and the optimal time for surgery are unknown.
Research motivation
To understand the best technique and timing of pancreas-preserving procedures for groove pancreatitis (GP).
Research objectives
To compare the results of conventional (Whipple procedure) and organ-preserving surgery for the treatment of GP.
Research methods
A retrospective comparison of the different conservative and surgical modalities for the treatment of GP in 84 patients.
Research results
Timely pancreas-preserving procedures for GP are safe and provide better long-term results compared to conventional surgery, which is usually used at the late stages of the disease.
Research conclusions
Pancreas-preserving duodenal resection (PPDR) may be the treatment of choice for the isolated form of GP; the pure form of GP is a disease of the duodenum, early detection of which makes preservation of the pancreas possible; prolonged conservative treatment in the isolated form of GP may lead to the development of segmental and diffuse pancreatitis, which may deprive patients of the pancreas-preserving option; timely performed PPDR is a treatment-changing procedure for GP.
Research perspectives
If the author’s approach is widely accepted, more patients with GP will have the chance to save their pancreas, and prospective comparative trials will be possible on the above mentioned subject.
