Published online Jul 27, 2020. doi: 10.4240/wjgs.v12.i7.326
Peer-review started: December 30, 2019
First decision: April 12, 2020
Revised: May 10, 2020
Accepted: May 15, 2020
Article in press: May 15, 2020
Published online: July 27, 2020
Postoperative acute kidney injury (AKI) is one of the most common complications after gastrointestinal and hepatobiliary surgery. Neutrophil-to-lymphocyte ratio (NLR) is a marker of inflammation that can be calculated directly from a patient's complete blood count. Extensive studies have shown that NLR can predict the outcome of cardiac surgery, sepsis, and cancer.
The risk factors and early diagnosis of postoperative AKI have always been urgent problems in clinic.
To clarify the relationship between NLR and the occurrence of AKI in patients with gastrointestinal and hepatobiliary surgery in the intensive care unit (ICU).
This study retrospectively analyzed the electronic medical records of 282 patients after gastrointestinal and hepatobiliary surgery in ICU to clarify the relationship between NLR at admission and the postoperative AKI occurrence.
Postoperative AKI occurred in 29.79% of patients receiving ICU care. NLR value at admission was higher in AKI patients compared with the non-AKI patients and increased with the severity of AKI. Patients with NLR ≥ 8.380 exhibited significantly higher incidences of postoperative AKI and severe AKI than patients with NLR < 8.380. The multivariate analysis showed that NLR at admission was an independent risk factor for occurrence of postoperative AKI in patients with gastrointestinal and hepatobiliary surgery in ICU.
NLR at admission is a predictor of AKI occurrence in patients with gastrointestinal and hepatobiliary surgery in ICU.
NLR should be included in the routine assessment of AKI occurrence.