Cotte E, Mohamed F, Nancey S, François Y, Glehen O, Flourié B, Saurin JC, Poncet G. Laparoscopic total colectomy: Does the indication influence the outcome? World J Gastrointest Surg 2011; 3(11): 177-182 [PMID: 22180834 DOI: 10.4240/wjgs.v3.i11.177]
Corresponding Author of This Article
Eddy Cotte, MD, PhD, Department of Digestive Surgery, Centre Hospitalo-Universitaire Lyon Sud, Hospices Civils de Lyon, 69495 Pierre Bénite Cedex, France. eddy.cotte@chu-lyon.fr
Article-Type of This Article
Brief Article
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Eddy Cotte, Yves François, Olivier Glehen, Department of Digestive Surgery, Centre Hospitalo-Universitaire Lyon Sud, Hospices Civils de Lyon, 69495 Pierre Bénite Cedex, France
Eddy Cotte, Yves François, Olivier Glehen, EA 3738, Université Claude Bernard Lyon1, Faculté de Médecine Lyon Sud, BP 12, 69921 Oullins Cedex, France
Faheez Mohamed, Colorectal Research Unit, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke RG24 9NA, Hampshire, United Kingdom
Stéphane Nancey, Bernard Flourié, Department of Gastroenterology, Centre Hospitalo-Universitaire Lyon-Sud, Hospices Civils de Lyon, 69495 Pierre Bénite Cedex, France
Jean-Christophe Saurin, Gilles Poncet, Digestive Federation, Centre Hospitalo-Universitaire Edouard Herriot, Hospices Civils de Lyon, 69008 Lyon, France
Author contributions: Cotte E and Poncet G analyzed the data and drafted the article; Mohamed F participated in the revision of article and checked the paper for linguistic accuracy; François Y, Glehen O and Saurin JC participated in the acquisition of the data and revision of the article; Nancey S and Flourié B participated in the interpretation of the data and revision of the article; all authors read and approved the final manuscript.
Correspondence to: Eddy Cotte, MD, PhD, Department of Digestive Surgery, Centre Hospitalo-Universitaire Lyon Sud, Hospices Civils de Lyon, 69495 Pierre Bénite Cedex, France. eddy.cotte@chu-lyon.fr
Telephone: +33-478-861385 Fax: +33-478-863343
Received: July 22, 2011 Revised: October 24, 2011 Accepted: October 29, 2011 Published online: November 27, 2011
Abstract
AIM: To assess and compare outcomes of laparoscopic total colectomy performed for a variety of indications.
METHODS: Sixty six patients underwent laparoscopic total colectomy for inflammatory bowel disease (IBD) (13) and other diseases (53). Data on demographics, pre- and post-operative outcomes were collected prospectively.
RESULTS: Mean operative time was 4.5 h. Conversion rate was 13.6%. Total colectomy performed for IBD was associated with a significantly higher anastomotic leak rate (23.1% vs 1.9%, P < 0.05). On univariate analysis, hand sewn anastomosis and treatment with more than 20 mg of prednisolone for at least 3 mo was associated with a higher anastomotic leak rate (P < 0.05). No significant difference was found in return of gut function and overall morbidity between disease groups.
CONCLUSION: Laparoscopic total colectomy is feasible and outcomes are equivalent whatever the indication, except for anastomotic leak rate which is higher for patients with IBD.
