Guidelines For Basic Research
Copyright ©2010 Baishideng. All rights reserved.
World J Gastrointest Surg. Apr 27, 2010; 2(4): 109-116
Published online Apr 27, 2010. doi: 10.4240/wjgs.v2.i4.109
Clinicopathologic and immunohistochemical profile of ovarian metastases from colorectal carcinoma
Gozde Kir, Ayse Gurbuz, Ates Karateke, Mustafa Kir
Gozde Kir, Department of Pathology, Umraniye Education and Research Hospital, Umraniye, Istanbul 34766, Turkey
Ayse Gurbuz, Ates Karateke, Department of Gynecology and Obstetrics, ZeynepKamil Women’s and Children Hospital, Istanbul 34668, Turkey
Mustafa Kir, Department of Gynecology and Obstetrics, Private Jinemed Hospital Istanbul 34357, Turkey
Author contributions: Kir G designed the review, collected the data, and drafted the manuscript; all authors approved the final manuscript.
Correspondence to: Gozde Kir, MD, Department of Pathology, Umraniye Education and Research Hospital, Umraniye, Istanbul 34766, Turkey. gozkir@yahoo.com
Telephone: +90-216-4494543 Fax: +90-216-4494842
Received: December 22, 2009
Revised: January 28, 2010
Accepted: February 4, 2010
Published online: April 27, 2010
Abstract

Metastasis of colorectal adenocarcinoma of the ovary is not an uncommon occurrence and ovarian metastases from colorectal carcinoma frequently mimic endometrioid and mucinous primary ovarian carcinoma. The clinical and pathologic features of metastatic colorectal adenocarcinoma involving the ovary is reviewed with particular focus on the diagnostic challenge of distinguishing these secondary ovarian tumors from primary ovarian neoplasm. Immunohistochemical stains that may be useful in the differential diagnosis of metastatic colorectal tumors to the ovary and primary ovarian tumors are detailed.

Keywords: Ovary, Colon, Metastatic carcinoma, Mucinous carcinoma, Colorectal carcinoma, Immunohistochemistry, Endometrioid adenocarcinoma