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Wang Y, Zhang T, Zhang XG, He JY, Wang ZY, Sun EH, Liu QQ, Zhang WJ. Clinical application of personalized biodegradable anastomotic stent via preoperative intestinal three-dimensions reconstruction in laparoscopic resection of rectal cancer. World J Gastrointest Surg 2026; 18(11): 122155 [DOI: 10.4240/wjgs.122155]
World J Gastrointest Surg. Nov 27, 2026; 18(11): 122155 Published online Nov 27, 2026. doi: 10.4240/wjgs.122155
Clinical application of personalized biodegradable anastomotic stent via preoperative intestinal three-dimensions reconstruction in laparoscopic resection of rectal cancer
Ying Wang, Xiao-Guang Zhang, Zhao-Yi Wang, En-Hui Sun, Qian-Qian Liu, Wen-Jie Zhang, Evaluation and Inspection Center, Tianjin Center of Medical Device Evaluation and Inspection, Tianjin 300384, China
Ting Zhang, Department of General Surgery, The 983rd Hospital of the Joint Logistics Support Force, Tianjin 300142, China
Jian-Ying He, Department of Cadre Wards, Tianjin Rehabilitation and Convalescence Center of Joint Logistic Support Force, Tianjin 300191, China
Co-first authors: Ying Wang and Ting Zhang.
Author contributions: Wang Y and Zhang T contributed equally to this study and are co-first authors, including the study design, data collection, statistical analysis, manuscript drafting and revision; Zhang XG, He JY, Wang ZY, Sun EH, and Liu QQ participated in data collection, literature review, and manuscript proofreading; WJ Zhang provided overall research guidance, supervised the study, and critically revised the manuscript. All the authors have read and approved the final version of the manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Institutional review board statement: This study has been reviewed and approved by the Medical Ethics Committee of Tianjin Center of Medical Device Evaluation and Inspection.
Informed consent statement: All the individuals who participated in this study provided their written informed consent prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Wen-Jie Zhang, Senior Researcher, Evaluation and Inspection Center, Tianjin Center of Medical Device Evaluation and Inspection, No. 237 Hongqi South Road, Nankai District, Tianjin 300384, China. paper_zwj@163.com
Received: May 15, 2026 Revised: June 16, 2026 Accepted: July 14, 2026 Published online: November 27, 2026 Processing time: 180 Days and 19.3 Hours
Abstract
BACKGROUND
Anastomotic complications affect postoperative recovery in patients with rectal cancer; therefore, more effective treatment strategies are urgently needed.
AIM
To analyze the clinical value of personalized biodegradable anastomotic reinforcement stents based on preoperative three-dimensional (3D) reconstruction parameters of the intestinal tract in laparoscopic anterior resection for rectal cancer.
METHODS
A total of 82 patients with rectal cancer who were admitted to our hospital between March 2023 and May 2025 were enrolled and divided into control and study groups according to the order of surgery. Both groups underwent laparoscopic anterior resection of the rectal cancer. The control group underwent conventional anastomosis, whereas the study group underwent implantation of personalized biodegradable anastomotic reinforcement stents based on the preoperative 3D reconstruction parameters of the intestinal tract. Perioperative indicators, postoperative recovery, anastomosis-related complications, postoperative inflammatory response levels and follow-up outcomes were compared between the two groups.
RESULTS
The stoma duration was longer in the study group than in the control group (P < 0.05). There were no significant differences in intraoperative blood loss, number of dissected lymph nodes, or conversion rate to open surgery between the two groups (P > 0.05). The time to first bowel sound recovery, time to first flatus, time to first oral intake, and time to first ambulation were shorter in the study group than in the control group (P < 0.05). The total incidence of anastomosis-related complications in the study group was 4.88% (2/41), which was lower than 21.95% (9/41) in the control group, with a significant difference (P < 0.05). The levels of inflammatory indicators at 1 day and 3 days after surgery in the study group were lower than those in the control group (P < 0.05). The Wexner incontinence and low anterior resection syndrome scores at 6 months and 12 months after surgery were significantly lower in the study group than in the control group (P < 0.05).
CONCLUSION
Implantation of personalized biodegradable anastomotic reinforcement stents based on preoperative 3D reconstruction parameters of the intestinal tract can promote postoperative intestinal function recovery, reduce the risk of anastomosis-related complications and inflammatory stimulation, and simultaneously improve postoperative defecation and anal function in patients undergoing laparoscopic anterior resection of rectal cancer.
Core Tip: Personalized biodegradable anastomotic reinforcement stents designed according to preoperative three-dimensional intestinal reconstruction parameters provide individualized mechanical support after laparoscopic anterior resection for rectal cancer. This study demonstrated that the stents accelerated postoperative bowel function recovery, reduced anastomosis-related complications and postoperative inflammatory responses, and improved long-term anorectal function. These findings suggest that patient-specific biodegradable reinforcement may represent a promising strategy for enhancing anastomotic healing and improving surgical outcomes in rectal cancer.
