Gu YJ, Chen ZT, Li QY. Stent placement can achieve same prognosis as endoscopic nasobiliary drainage in treatment of bile leakage after liver transplantation. World J Gastrointest Surg 2025; 17(5): 104191 [DOI: 10.4240/wjgs.v17.i5.104191]
Corresponding Author of This Article
Qi-Yong Li, MD, PhD, Chief Doctor, Department of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, No. 848 Dongxin Road, Hangzhou 310000, Zhejiang Province, China. zjliqiyong@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. May 27, 2025; 17(5): 104191 Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.104191
Stent placement can achieve same prognosis as endoscopic nasobiliary drainage in treatment of bile leakage after liver transplantation
Yang-Jun Gu, Zhi-Tao Chen, Qi-Yong Li
Yang-Jun Gu, Zhi-Tao Chen, Qi-Yong Li, Department of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou 310000, Zhejiang Province, China
Author contributions: Gu YJ collected the data, performed statistical analysis, and drafted the manuscript; Chen ZT participated in the data collection; Li QY contributed to study concept and design, checked the data and revised the manuscript; and all authors have read and approved the final manuscript.
Institutional review board statement: This research was approved by the Clinical Trial Ethics Review Committee of Shulan (Hangzhou) Hospital (No. KY2023063) and all methods were performed in accordance with the relevant guidelines and regulations.
Informed consent statement: This study was a retrospective study, which was reviewed by the institutional ethics committee and exempted from individual informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated and/or analyzed during the current study are not publicly available due to protect the privacy of the patient but are available from the corresponding author on reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qi-Yong Li, MD, PhD, Chief Doctor, Department of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, No. 848 Dongxin Road, Hangzhou 310000, Zhejiang Province, China. zjliqiyong@163.com
Received: December 13, 2024 Revised: March 17, 2025 Accepted: April 3, 2025 Published online: May 27, 2025 Processing time: 161 Days and 12.9 Hours
Abstract
BACKGROUND
Both stent placement and endoscopic nasobiliary drainage (ENBD) are commonly used for treating bile leakage following liver transplantation. However, little research has compared the advantages of both methods.
AIM
To compare the prognosis of stent placement and ENBD in treating bile leakage following liver transplantation.
METHODS
We retrospectively collected data for patients with bile leakage after liver transplantation in our center. The efficiency and prognosis were compared between the stent placement and ENBD groups.
RESULTS
We retrospectively collected data from 50 patients diagnosed with bile leakage within 1 month after liver transplantation. Forty patients underwent ENBD and nine received stent placement. Baseline patient characteristics, except white blood cell count, total bilirubin and direct bilirubin levels, were comparable between the two groups. Additionally, there was no significant difference in the rates of reconveyance or postoperative biliary stricture.
CONCLUSION
Stent placement and ENBD are recommended for treating bile leakage after liver transplantation, with similar efficacy and prognosis.
Core Tip: Both stent placement and endoscopic nasobiliary drainage are effective for treating bile leakage after liver transplantation, with comparable efficacy and prognosis. Our retrospective study of 50 patients showed no significant differences in outcomes, except for variations in white blood cell count and bilirubin levels. Both methods are recommended based on similar success rates and post-operative complications.
